Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 6/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 3/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | FYN | P06241 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2311992 | 1.00 | SLC7A5 (0.51) | SLC7A5ALOX15KDM4ERECQLHIF1A | |
| SCHEMBL3411781 | 1.00 | SLC7A5 (0.51) | SLC7A5ALOX15KDM4ERECQLHIF1A | |
| SCHEMBL1172012 | 0.95 | SLC7A5 (0.46) | SLC7A5ALOX15KDM4ERECQLHIF1A | |
| SCHEMBL8230342 | 0.91 | SLC7A5 (0.40) | SLC7A5ALOX15KDM4ERECQLHIF1A | |
| SCHEMBL3412205 | 0.91 | SLC7A5 (0.51) | SLC7A5ALOX15KDM4ERECQLHIF1A | |
| SCHEMBL15120465 | 0.88 | ALOX15 (0.42) | SLC7A5ALOX15KDM4ERECQLHIF1A | |
| SCHEMBL12646488 | 0.84 | LCK (0.42) | SLC7A5ALOX15KDM4ERECQLHIF1A | |
| SCHEMBL9883712 | 0.84 | LCK (0.42) | SLC7A5ALOX15KDM4ERECQLHIF1A | |
| SCHEMBL11750741 | 0.83 | ALOX15 (0.60) | SLC7A5ALOX15KDM4ERECQLHIF1A | |
| SCHEMBL12646479 | 0.81 | CA1 (0.40) | ALOX15KDM4ERECQLHIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1959948-B1 | LEVODOPA PRODRUG MESYLATE, COMPOSITIONS THEREOF, AND USES THEREOF | XENOPORT INC (US) | 2012-07-18 | — | — | EP | claimed |