Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2311992 | 0.91 | SLC7A5 (0.51) | SLC7A5KDM4EUSP2EGFRLCK | |
| SCHEMBL3411781 | 0.91 | SLC7A5 (0.51) | SLC7A5KDM4EUSP2EGFRLCK | |
| SCHEMBL10318019 | 0.91 | SLC7A5 (0.51) | SLC7A5KDM4EUSP2EGFRLCK | |
| SCHEMBL1172012 | 0.86 | SLC7A5 (0.46) | SLC7A5KDM4EUSP2EGFRLCK | |
| SCHEMBL3412205 | 0.82 | SLC7A5 (0.51) | SLC7A5KDM4EUSP2EGFRLCK | |
| SCHEMBL15120465 | 0.80 | ALOX15 (0.42) | SLC7A5KDM4EUSP2EGFRLCK | |
| SCHEMBL14617681 | 0.79 | SLC7A5 (0.48) | SLC7A5KDM4EUSP2EGFRLCK | |
| SCHEMBL12646488 | 0.76 | LCK (0.42) | SLC7A5KDM4EUSP2EGFRLCK | |
| SCHEMBL9883712 | 0.76 | LCK (0.42) | SLC7A5KDM4EUSP2EGFRLCK | |
| SCHEMBL9958437 | 0.74 | ALDH1A1 (0.52) | SLC7A5KDM4EUSP2EGFRLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007067495-A2 | LEVODOPA PRODRUG MESYLATE, COMPOSITIONS THEREOF, AND USES THEREOF | XENOPORT, INC. (US) | 2007-06-14 | — | — | WO | disclosed |