Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31549911 | 1.00 | TDP1 (0.53) | TDP1ALDH1A1L3MBTL1KDM4EPOLB | |
| SCHEMBL1961457 | 0.86 | TDP1 (0.63) | TDP1ALDH1A1L3MBTL1KDM4EPOLB | |
| SCHEMBL2494137 | 0.82 | TDP1 (0.51) | TDP1ALDH1A1L3MBTL1KDM4EPOLB | |
| SCHEMBL30439274 | 0.82 | TDP1 (0.51) | TDP1ALDH1A1L3MBTL1KDM4EPOLB | |
| Methyl Alcohol SCHEMBL27781923 | 0.82 | TDP1 (0.59) | TDP1ALDH1A1L3MBTL1KDM4EPOLB | |
| SCHEMBL9452627 | 0.81 | ALDH1A1 (0.52) | TDP1ALDH1A1TSHR | |
| SCHEMBL20489366 | 0.81 | TDP1 (0.53) | TDP1ALDH1A1L3MBTL1KDM4EPOLB | |
| SCHEMBL30729936 | 0.81 | PDE7A (0.49) | TDP1ALDH1A1L3MBTL1KDM4EPOLB | |
| SCHEMBL27184243 | 0.81 | PDE7A (0.49) | TDP1ALDH1A1L3MBTL1KDM4EPOLB | |
| SCHEMBL16590518 | 0.80 | TDP1 (0.57) | TDP1ALDH1A1L3MBTL1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109265350-A | The synthetic method of acaricide Bifenazate intermediate 3- nitro -4- methoxyl biphenyl | 山东省农药科学研究院 | 2019-01-25 | — | — | CN | claimed |
| CN-105273324-A | Flame retardant used for high glow wires and preparation method thereof | NINGXIA RUNLONG PACKAGING MATERIAL CO LTD | 2016-01-27 | — | — | CN | claimed |
| WO-2024219864-A1 | NOVEL COMPOUND EXHIBITING SETDB1 INHIBITORY ACTIVITY, AND USE THEREOF | 주식회사 넷타겟 | 2024-10-24 | — | — | WO | disclosed |
| US-20240101548-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD (CN) | 2024-03-28 | — | — | US | disclosed |
| US-11744144-B2 | Organic electroluminescent element, light-emitting material therefor, light emitting device, display device, and illumination device | UDC IRELAND LIMITED (IE) | 2023-08-29 | — | — | US | disclosed |
| CN-113582907-A | Preparation method of 5-hydrogen-benzo [ B ] carbazole derivative and derivative thereof | 陕西维世诺新材料有限公司 | 2021-11-02 | — | — | CN | disclosed |
| US-11053205-B2 | Phenazine derivatives as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-07-06 | — | — | US | disclosed |
| CN-107973727-B | M-disubstituted phenol compound, preparation method and anti-tubercle bacillus application thereof | 中山大学 | 2020-04-17 | — | — | CN | disclosed |
| CN-109912437-A | A kind of polyamine monomers and preparation method thereof, a kind of polyimides and preparation method thereof and a kind of Kapton | 吉林大学 | 2019-06-21 | — | — | CN | disclosed |
| CN-109265350-A | The synthetic method of acaricide Bifenazate intermediate 3- nitro -4- methoxyl biphenyl | 山东省农药科学研究院 | 2019-01-25 | — | — | CN | disclosed |
| EP-3053984-B1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME | LG CHEMICAL LTD (KR) | 2018-10-31 | — | — | EP | disclosed |
| US-20120277237-A1 | NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMA SA (CH) | 2012-11-01 | — | — | US | disclosed |
| EP-2426115-A2 | Alkynyl derivatives as modulators of metabotropic glutamate receptors | Addex Pharma SA (CH) | 2012-03-07 | — | — | EP | disclosed |
| US-8101637-B2 | Alkynyl derivatives as modulators of metatropic glutamate receptors | ADDEX PHARMA SA (CH) | 2012-01-24 | — | — | US | disclosed |
| CN-102170882-A | Compositions and methods of treating amyloid disease | TREVENTIS CORP | 2011-08-31 | — | — | CN | disclosed |
| WO-2010049731-A1 | PYRAZOLO- AND IMIDAZOPYRIDINYLPYRIMIDINEAMINES AS IGF-1R TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2010-05-06 | — | — | WO | disclosed |
| US-20090124625-A1 | NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METATROPIC GLUTAMATE RECEPTORS | ADDEX PHARMACEUTICALS SA (CH) | 2009-05-14 | — | — | US | disclosed |
| EP-1765795-A2 | ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | Addex Pharmaceuticals SA (CH) | 2007-03-28 | — | — | EP | disclosed |
| CN-1791600-A | Benzothiazole derivatives as adenosine receptor ligands | HOFFMANN LA ROCHE (CH) | 2006-06-21 | — | — | CN | disclosed |
| WO-2005123703-A2 | ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMACEUTICALS SA (CH) | 2005-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240101548-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | TYK2, WEE2, WEE1 | TDP1 1205/4885ALDH1A1 3779/4885L3MBTL1 4252/4885 |
| US-20090124625-A1 | NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METATROPIC GLUTAMATE RECEPTORS | GRM5, GRM2, GRM1 | TDP1 3469/4885ALDH1A1 2496/4885L3MBTL1 4070/4885 |
| US-20120277237-A1 | NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | GRM5, GRM1, GRM2 | TDP1 2938/4885ALDH1A1 2153/4885L3MBTL1 3907/4885 |
| US-11053205-B2 | Phenazine derivatives as antimicrobial agents | ROS1, NOX4, PRDX3 | TDP1 3827/4885ALDH1A1 701/4885L3MBTL1 4638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.