Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 3/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.45 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.45 |
| ▸ | AKT1 | P31749 | 2/20 | 0.45 |
| ▸ | NEK4 | P51957 | 2/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.45 |
| ▸ | PRKG2 | Q13237 | 2/20 | 0.45 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.45 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.45 |
| ▸ | GSK3A | P49840 | 2/20 | 0.45 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10318762 | 1.00 | TAS1R3 (0.50) | TAS1R3TAS1R1ROCK1ROCK2DYRK1A | |
| SCHEMBL10317811 | 1.00 | TAS1R3 (0.50) | TAS1R3TAS1R1ROCK1ROCK2DYRK1A | |
| Trifluoroacetic Acid SCHEMBL10319963 | 0.93 | TAS1R3 (0.45) | TAS1R3TAS1R1ROCK1ROCK2DYRK1A | |
| Trifluoroacetic Acid SCHEMBL10321622 | 0.93 | TAS1R3 (0.45) | TAS1R3TAS1R1ROCK1ROCK2DYRK1A | |
| SCHEMBL10318421 | 0.90 | ROCK1 (0.58) | TAS1R3TAS1R1ROCK1ROCK2DYRK1A | |
| SCHEMBL10322648 | 0.87 | DYRK1A (0.47) | ROCK1ROCK2DYRK1ADYRK1BMAPK1 | |
| SCHEMBL10317809 | 0.85 | TAS1R3 (0.48) | TAS1R3TAS1R1ROCK1ROCK2DYRK1A | |
| SCHEMBL10318759 | 0.85 | TAS1R3 (0.48) | TAS1R3TAS1R1ROCK1ROCK2DYRK1A | |
| SCHEMBL10320708 | 0.85 | TAS1R3 (0.48) | TAS1R3TAS1R1ROCK1ROCK2DYRK1A | |
| SCHEMBL10321531 | 0.85 | DYRK1A (0.51) | DYRK1ADYRK1BKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120184548-A1 | CARBOXYLIC ACID ARYL AMIDES | DOMINIQUE ROMYR (US) | 2012-07-19 | — | — | US | claimed |
| US-20120184548-A1 | CARBOXYLIC ACID ARYL AMIDES | DOMINIQUE ROMYR (US) | 2012-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184548-A1 | CARBOXYLIC ACID ARYL AMIDES | GOT1, PPARG, PPARA | TAS1R3 4487/4885TAS1R1 4348/4885ROCK1 4062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.