⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941730 | 0.86 | CA1 (0.35) | — | |
| SCHEMBL1145502 | 0.83 | — | — | |
| SCHEMBL797340 | 0.76 | — | — | |
| SCHEMBL11455861 | 0.72 | — | — | |
| SCHEMBL895220 | 0.69 | — | — | |
| SCHEMBL8758 | 0.69 | — | — | |
| SCHEMBL1031340 | 0.69 | — | — | |
| SCHEMBL9542238 | 0.69 | — | — | |
| SCHEMBL11801827 | 0.67 | — | — | |
| SCHEMBL1647723 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275758-A1 | PROCESS FOR PHENYLACETIC ACID DERIVATIVES | NOVARTIS AG (CH) | 2009-11-05 | — | — | US | claimed |
| US-20080249318-A1 | Process for phenylacetic acid derivatives | ACEMOGLU MURAT | 2008-10-09 | — | — | US | claimed |
| JP-2003510303-A | — | — | 2003-03-18 | — | — | JP | claimed |
| EP-1216226-A2 | PROCESS FOR PHENYLACETIC ACID DERIVATIVES | Novartis AG (CH) | 2002-06-26 | — | — | EP | claimed |
| WO-2001023346-A2 | PROCESS FOR PHENYLACETIC ACID DERIVATIVES | NOVARTIS AG (CH) | 2001-04-05 | — | — | WO | claimed |
| US-12421178-B2 | Non-cryogenic, ammonia-free reduction of aryl compounds | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2025-09-23 | — | — | US | disclosed |
| US-20240092708-A1 | Non-Cryogenic, Ammonia-Free Reduction of Aryl Compounds | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2024-03-21 | — | — | US | disclosed |
| US-11866386-B2 | Non-cryogenic, ammonia-free reduction of aryl compounds | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2024-01-09 | — | — | US | disclosed |
| US-20220089508-A1 | Non-Cryogenic, Ammonia-Free Reduction of Aryl Compounds | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2022-03-24 | — | — | US | disclosed |
| US-7906677-B2 | Process for phenylacetic acid derivatives | NOVARTIS AG (CH) | 2011-03-15 | — | — | US | disclosed |
| US-7906677-B2 | Process for phenylacetic acid derivatives | NOVARTIS AG (CH) | 2011-03-15 | — | — | US | disclosed |
| US-7906677-B2 | Process for phenylacetic acid derivatives | NOVARTIS AG (CH) | 2011-03-15 | — | — | US | disclosed |
| WO-2001014355-A1 | SUBSTITUTED PIPERAZINE DERIVATIVES, THE PRODUCTION THEREOF AND THEIR UTILIZATION AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-01 | — | — | WO | disclosed |
| US-4670041-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-06-02 | — | — | US | disclosed |
| EP-0081893-B1 | OXABICYCLOALKANE HERBICIDES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-03-04 | — | — | EP | disclosed |
| US-4567283-A | EPOXYCYCLOHEXANOLS | SHELL OIL COMPANY (US) | 1986-01-28 | — | — | US | disclosed |
| US-4554366-A | HERBICIDES, PLANT GROWTH REGULATORS | SHELL OIL COMPANY (US) | 1985-11-19 | — | — | US | disclosed |
| US-4542244-A | Oxabicycloalkane herbicides | SHELL OIL COMPANY (US) | 1985-09-17 | — | — | US | disclosed |
| EP-0081893-A2 | Oxabicycloalkane herbicides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1983-06-22 | — | — | EP | disclosed |
| US-4231928-A | 6-(7-HYDROXY-4-OXO-4H-PYRIMIDO(1,2-B)PYRIDAZIN-3-YL-CARBOXAMIDO) SUBSTITUTED PENICILLINS | BRISTOL-MYERS COMPANY (US) | 1980-11-04 | — | — | US | disclosed |