⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202710 | 0.80 | — | — | |
| SCHEMBL8941730 | 0.76 | CA1 (0.35) | — | |
| SCHEMBL1145502 | 0.74 | — | — | |
| SCHEMBL12084338 | 0.71 | LMNA (0.32) | — | |
| SCHEMBL11807487 | 0.67 | — | — | |
| SCHEMBL1032152 | 0.66 | — | — | |
| SCHEMBL11801827 | 0.64 | — | — | |
| SCHEMBL7328006 | 0.61 | — | — | |
| SCHEMBL1031340 | 0.61 | — | — | |
| SCHEMBL17066828 | 0.60 | PPARG (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0096480-B1 | PREPARATION OF 6A, 10A-TRANS-HEXAHYDRODIBENZOPYRANONES | ELI LILLY AND COMPANY (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0096480-A2 | Preparation of 6a, 10a-trans-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1983-12-21 | — | — | EP | claimed |
| US-4148809-A | Process for preparing dl-cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones | ELI LILLY AND COMPANY (US) | 1979-04-10 | — | — | US | claimed |
| US-4131614-A | Process for preparing cis-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1978-12-26 | — | — | US | claimed |
| US-20210163387-A1 | ONE-STEP FLOW-MEDIATED SYNTHESIS OF CANNABIDIOL (CBD) AND DERIVATIVES | TRUSTEES OF BOSTON UNIVERSITY (US) | 2021-06-03 | — | — | US | disclosed |
| US-10981850-B2 | One-step flow-mediated synthesis of cannabidiol (CBD) and derivatives | TRUSTEES OF BOSTON UNIVERSITY (US) | 2021-04-20 | — | — | US | disclosed |
| US-20200325091-A1 | ONE-STEP FLOW-MEDIATED SYNTHESIS OF CANNABIDIOL (CBD) AND DERIVATIVES | TRUSTEES OF BOSTON UNIVERSITY (US) | 2020-10-15 | — | — | US | disclosed |
| EP-2314580-B1 | Method for producing synthetic cannabinoids | HEALTH CONCEPT GMBH (DE) | 2015-09-09 | — | — | EP | disclosed |
| CN-104479771-A | Composition for inhibiting alcohol-based fuel for boilers from producing nitrogen oxides | SHANXI WHARTON IND CO LTD | 2015-04-01 | — | — | CN | disclosed |
| US-8258322-B2 | Synthesis of hexahydrodibenzopyranones | WATSON LABORATORIES, INC. (US) | 2012-09-04 | — | — | US | disclosed |
| US-8258322-B2 | Synthesis of hexahydrodibenzopyranones | WATSON LABORATORIES, INC. (US) | 2012-09-04 | — | — | US | disclosed |
| US-8258322-B2 | Synthesis of hexahydrodibenzopyranones | WATSON LABORATORIES, INC. (US) | 2012-09-04 | — | — | US | disclosed |
| US-4171315-A | Preparation of cis-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1979-10-16 | — | — | US | disclosed |
| US-4148809-A | Process for preparing dl-cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones | ELI LILLY AND COMPANY (US) | 1979-04-10 | — | — | US | disclosed |
| US-4140701-A | 2,6-Methano-2H-1-benzoxocins | ELI LILLY AND COMPANY (US) | 1979-02-20 | — | — | US | disclosed |
| US-4133816-A | Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones and intermediates therefor | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4131614-A | Process for preparing cis-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1978-12-26 | — | — | US | disclosed |
| US-4054581-A | Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones and intermediates therefor | ELI LILLY AND COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
| US-4054583-A | Process for converting 2,7-dihydroxy-5-isopropylidene-9-substituted-2,6-methano-3,4,5,6-tetrahydro-2H-1-benzoxocin to trans-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo(b,d)pyran-9-one | ELI LILLY AND COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
| US-4054582-A | Process for converting cis-hexahydrodibenzo[b,d]pyran-9-ones to trans-hexahydrodibenzo[b,d]-pyran-9-ones | ELI LILLY AND COMPANY (US) | 1977-10-18 | — | — | US | disclosed |