Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 3/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3301557 | 0.96 | ALDH1A1 (0.34) | KEAP1NFE2L2ALDH1A1USP2TSHR | |
| SCHEMBL13390727 | 0.87 | TSHR (0.32) | ALDH1A1USP2TSHR | |
| SCHEMBL4432779 | 0.86 | KEAP1 (0.35) | KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL3298686 | 0.85 | KEAP1 (0.35) | KEAP1NFE2L2ALDH1A1USP2TSHR | |
| SCHEMBL10318086 | 0.83 | KEAP1 (0.36) | KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL4430841 | 0.81 | KEAP1 (0.39) | KEAP1NFE2L2ALDH1A1USP2TSHR | |
| SCHEMBL13409227 | 0.81 | PTGDR2 (0.31) | — | |
| SCHEMBL3298220 | 0.81 | ALDH1A1 (0.34) | KEAP1NFE2L2ALDH1A1USP2TSHR | |
| SCHEMBL3300839 | 0.81 | KEAP1 (0.35) | KEAP1NFE2L2ALDH1A1USP2TSHR | |
| SCHEMBL3298351 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121600-B1 | SUBSTITUTED ARYLSULPHONYLGLYCINES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INT (DE) | 2012-07-18 | — | — | EP | disclosed |