Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 6/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 4/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10323913 | 0.79 | TPMT (0.41) | TPMTCA12CA1CA2CA4 | |
| SCHEMBL10322116 | 0.79 | TPMT (0.58) | TPMTCA12CA1CA2CA4 | |
| SCHEMBL10322869 | 0.78 | ERN1 (0.51) | CA1CA2ERN1MAOB | |
| SCHEMBL29381794 | 0.77 | HTT (0.47) | TPMTCA12CA1CA2CA4 | |
| SCHEMBL22466026 | 0.77 | HTT (0.47) | TPMTCA12CA1CA2CA4 | |
| SCHEMBL10323635 | 0.76 | TPMT (0.44) | TPMTCA12CA1CA2CA4 | |
| SCHEMBL3547114 | 0.75 | PPARG (0.45) | TPMTCA12CA1CA2CA4 | |
| SCHEMBL3548180 | 0.74 | TPMT (0.53) | TPMTCA12CA1CA2CA4 | |
| SCHEMBL3548177 | 0.74 | TPMT (0.53) | TPMTCA12CA1CA2CA4 | |
| SCHEMBL1302354 | 0.74 | TPMT (0.63) | TPMTCA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2484669-B1 | PHENOL DERIVATIVES | FUJI YAKUHIN CO LTD (JP) | 2015-07-29 | — | — | EP | disclosed |
| US-8367843-B2 | Phenol derivative | FUJI YAKUHIN CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| EP-2484669-A1 | NOVEL PHENOL DERIVATIVE | Fuji Yakuhin Co., Ltd. (JP) | 2012-08-08 | — | — | EP | disclosed |
| US-20120184587-A1 | NOVEL PHENOL DERIVATIVE | FUJI YAKUHIN CO., LTD. (JP) | 2012-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184587-A1 | NOVEL PHENOL DERIVATIVE | XDH, REN, UTS2R | TPMT 193/4885CA12 2377/4885CA1 2558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.