Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1029572 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL1031983 | 0.87 | NISCH (0.33) | — | |
| Hydrochloric Acid SCHEMBL1032780 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL1028633 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL1032740 | 0.80 | KIF11 (0.30) | — | |
| Hydrochloric Acid SCHEMBL1028611 | 0.80 | PDE4A (0.32) | — | |
| Hydrochloric Acid SCHEMBL1032929 | 0.79 | MEN1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL1030034 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL1029389 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL1032171 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567560-B1 | ORGANOMETALLIC TRANSITION METAL COMPOUND, BISCYCLOPENTADIENYL LIGAND SYSTEM, CATALYST SYSTEM AND PROCESS FOR PREPARING POLYOLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2011-01-19 | — | — | EP | disclosed |
| US-7405261-B2 | Organometallic transition metal compound, biscyclopentadienyl ligand system, catalyst system and process for preparing polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2008-07-29 | — | — | US | disclosed |
| US-20060122345-A1 | Organometallic transition metal compound, biscyclopentadienyl ligand system, catalyst system and process for preparing polyolefins | BASSELL POLYOLEFINE GMBH (DE) | 2006-06-08 | — | — | US | disclosed |