Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11112327 | 0.77 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL10447738 | 0.77 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL22644428 | 0.73 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL12640263 | 0.72 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL3672534 | 0.69 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL6300536 | 0.69 | HSP90AB1 (0.39) | ALDH1A1 | |
| SCHEMBL21076821 | 0.69 | CDK2 (0.50) | CCNA2CDK2CCNA1ALDH1A1 | |
| SCHEMBL6335694 | 0.69 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL9288161 | 0.68 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL31192804 | 0.67 | CYP1A2 (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332859-B | Hydrazone compound and preparation method and application thereof | 华中师范大学 | 2025-02-25 | — | — | CN | disclosed |
| CN-116332859-A | Hydrazone compound and preparation method and application thereof | 华中师范大学 | 2023-06-27 | — | — | CN | disclosed |
| WO-2012098065-A1 | PYRIDO PYRIMIDINES FOR USE AS DYRK1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-07-26 | — | — | WO | disclosed |
| US-20120184542-A1 | PYRIDO PYRIMIDINES | ANDERSON KEVIN (US) | 2012-07-19 | — | — | US | disclosed |
| US-20120184542-A1 | PYRIDO PYRIMIDINES | ANDERSON KEVIN (US) | 2012-07-19 | — | — | US | disclosed |
| US-20120184542-A1 | PYRIDO PYRIMIDINES | ANDERSON KEVIN (US) | 2012-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184542-A1 | PYRIDO PYRIMIDINES | TYMS, TYMP, DPYD | CCNA2 147/4885CDK2 30/4885CCNA1 153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.