Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5400972 | 0.88 | CYP1A2 (0.46) | CYP1A2MAPTKDM4ENPSR1LMNA | |
| SCHEMBL6335694 | 0.74 | ALDH1A1 (0.37) | CYP1A2MAPTLMNAALDH1A1TDP1 | |
| SCHEMBL114532 | 0.73 | MAPT (0.40) | CYP1A2MAPTKDM4ENPSR1LMNA | |
| SCHEMBL2115445 | 0.72 | CYP1A2 (0.68) | CYP1A2MAPTLMNARECQLMEN1 | |
| SCHEMBL55347 | 0.72 | ALDH1A1 (0.39) | MAPTKDM4ENPSR1LMNARECQL | |
| SCHEMBL23179859 | 0.71 | GAA (0.44) | MAPTKDM4ELMNAKMT2ARAB9A | |
| SCHEMBL31582903 | 0.71 | LMNA (0.38) | CYP1A2MAPTKDM4ENPSR1LMNA | |
| SCHEMBL275910 | 0.70 | CYP1A2 (0.48) | CYP1A2MAPTLMNARECQLMEN1 | |
| SCHEMBL275004 | 0.70 | CYP1A2 (0.48) | CYP1A2MAPTRECQLMEN1KMT2A | |
| SCHEMBL192661 | 0.70 | LMNA (0.55) | MAPTKDM4ENPSR1LMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024177126-A1 | 6-ALKOXYPYRAZOLOPYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | 日本たばこ産業株式会社 | 2024-08-29 | — | — | WO | disclosed |