SCHEMBL10322973

SCHEMBL10322973

CC(=O)c1ccc(O)c(OC(F)(F)F)c1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
APP P05067 8/20 0.50
SLC22A6 Q4U2R8 1/20 0.47
SLC22A8 Q8TCC7 1/20 0.47
MEN1 O00255 1/20 0.47
RAB9A P51151 1/20 0.47
KMT2A Q03164 1/20 0.47
HTT P42858 2/20 0.46
PKM P14618 1/20 0.46
GCGR P47871 1/20 0.44
ESRRA P11474 2/20 0.42
LMNA P02545 1/20 0.42
HSD17B2 P37059 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24436714 0.86 EPHX2 (0.44) APPMEN1KMT2AHTTPKM
SCHEMBL3648979 0.84 HTT (0.61) APPSLC22A6SLC22A8MEN1RAB9A
SCHEMBL10321468 0.83 CA12 (0.59) APPSLC22A6SLC22A8MEN1RAB9A
SCHEMBL2796916 0.83 EPHX2 (0.47) LMNA
SCHEMBL30975811 0.83 EPHX2 (0.47) LMNA
SCHEMBL17407195 0.83 NOTUM (0.54) MEN1RAB9AKMT2ALMNA
SCHEMBL3641624 0.83 APP (0.50) APPSLC22A6SLC22A8MEN1RAB9A
SCHEMBL24436791 0.82 APP (0.50) APPSLC22A6SLC22A8MEN1RAB9A
SCHEMBL24812330 0.81 CYP1A2 (0.53) MEN1KMT2ALMNA
SCHEMBL20702550 0.81 NOTUM (0.42) ESRRALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4001336-A1 POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE Shin-Etsu Chemical Co., Ltd. (JP) 2022-05-25 EP disclosed
US-20220157484-A1 POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-05-19 US disclosed
EP-2484669-B1 PHENOL DERIVATIVES FUJI YAKUHIN CO LTD (JP) 2015-07-29 EP disclosed
US-8367843-B2 Phenol derivative FUJI YAKUHIN CO., LTD. (JP) 2013-02-05 US disclosed
EP-2484669-A1 NOVEL PHENOL DERIVATIVE Fuji Yakuhin Co., Ltd. (JP) 2012-08-08 EP disclosed
US-20120184587-A1 NOVEL PHENOL DERIVATIVE FUJI YAKUHIN CO., LTD. (JP) 2012-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120184587-A1 NOVEL PHENOL DERIVATIVE XDH, REN, UTS2R APP 4701/4885SLC22A6 210/4885SLC22A8 69/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.