Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ADCYAP1R1 | P41586 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10429197 | 0.92 | GLRA1 (0.64) | KDM4EGLRA1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10323084 | 0.91 | KDM4E (0.64) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL4901522 | 0.87 | GLRA1 (0.65) | KDM4EGLRA1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL3229895 | 0.87 | KDM4E (0.60) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL29136484 | 0.87 | HPGD (0.63) | KDM4EGLRA1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3227053 | 0.86 | KDM4E (0.62) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL31192445 | 0.86 | KDM4E (0.59) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL31192441 | 0.85 | KDM4E (0.64) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL11345190 | 0.83 | GLRA1 (0.60) | KDM4EGLRA1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10324062 | 0.83 | GLRA1 (0.54) | KDM4EGLRA1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2484669-B1 | PHENOL DERIVATIVES | FUJI YAKUHIN CO LTD (JP) | 2015-07-29 | — | — | EP | disclosed |
| CN-102639518-B | Novel Phenol Derivatives | FUJI YAKUHIN CO LTD | 2015-03-25 | — | — | CN | disclosed |
| US-8367843-B2 | Phenol derivative | FUJI YAKUHIN CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| CN-102639518-A | Novel Phenol Derivatives | FUJI YAKUHIN CO LTD | 2012-08-15 | — | — | CN | disclosed |
| EP-2484669-A1 | NOVEL PHENOL DERIVATIVE | Fuji Yakuhin Co., Ltd. (JP) | 2012-08-08 | — | — | EP | disclosed |
| US-20120184587-A1 | NOVEL PHENOL DERIVATIVE | FUJI YAKUHIN CO., LTD. (JP) | 2012-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184587-A1 | NOVEL PHENOL DERIVATIVE | XDH, REN, UTS2R | KDM4E 2141/4885GLRA1 2739/4885SMN1; SMN2 3904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.