SCHEMBL10323716

SCHEMBL10323716

[c]1c(Cc2ccccc2)c(Cc2ccccc2)cc(Cc2ccccc2)c1Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.50
BCL2L1 Q07817 1/20 0.50
CALM1 P0DP23 1/20 0.48
ALOX5 P09917 1/20 0.44
HTR2A P28223 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CYP3A4 P08684 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
HIF1A Q16665 1/20 0.41
HSD17B10 Q99714 1/20 0.41
PTPN1 P18031 2/20 0.38
PTPN2 P17706 1/20 0.38
PTPN6 P29350 1/20 0.38
IDH1 O75874 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10384790 0.83 CALM1 (0.61) BCL2BCL2L1CALM1HTR2ACYP3A4
SCHEMBL9128868 0.82 BCL2 (0.42) BCL2BCL2L1CALM1ALOX5HTR2A
SCHEMBL5482676 0.80 BCL2 (0.71) BCL2BCL2L1CALM1ALOX5HTR2A
SCHEMBL10322337 0.77 CALM1 (0.42) BCL2BCL2L1CALM1ALOX5HTR2A
SCHEMBL10322438 0.75 CALM1 (0.46) BCL2BCL2L1CALM1ALOX5HTR2A
SCHEMBL10322357 0.74 CALM1 (0.50) BCL2BCL2L1CALM1HTR2ACYP3A4
SCHEMBL10323235 0.72 BCL2 (0.41) BCL2BCL2L1CALM1ALOX5HTR2A
SCHEMBL972711 0.72 CALM1 (0.69) BCL2BCL2L1CALM1ALOX5HTR2A
SCHEMBL28593839 0.71 BCL2 (0.54) BCL2BCL2L1CALM1ALOX5HTR2A
SCHEMBL10575256 0.71 BCL2 (0.48) BCL2BCL2L1CALM1HTR2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120184693-A1 ETHYLENE POLYMER PREPARATION METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-19 US disclosed