SCHEMBL10322337

SCHEMBL10322337

[c]1c(Cc2ccccc2)ccc(Cc2ccccc2)c1Cc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.42
BCL2 P10415 1/20 0.41
BCL2L1 Q07817 1/20 0.41
ALOX5 P09917 1/20 0.40
HTR2A P28223 1/20 0.38
CTRC Q99895 3/20 0.37
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
CYP3A4 P08684 1/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
HIF1A Q16665 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10323716 0.77 BCL2 (0.50) CALM1BCL2BCL2L1ALOX5HTR2A
SCHEMBL10323235 0.76 BCL2 (0.41) CALM1BCL2BCL2L1ALOX5HTR2A
SCHEMBL207607 0.73 CALM1 (0.55) CALM1BCL2BCL2L1HTR2ACYP3A4
SCHEMBL10384790 0.73 CALM1 (0.61) CALM1BCL2BCL2L1HTR2ACYP3A4
SCHEMBL721135 0.69 CALM1 (0.44) CALM1BCL2BCL2L1ALOX5HTR2A
SCHEMBL9128868 0.69 BCL2 (0.42) CALM1BCL2BCL2L1ALOX5HTR2A
SCHEMBL8670274 0.68 APOBEC3A (0.41) CALM1BCL2BCL2L1HTR2AHIF1A
SCHEMBL27500352 0.68 CALM1 (0.42) CALM1BCL2BCL2L1CTRCMEN1
SCHEMBL852825 0.68 CALM1 (0.42) CALM1BCL2BCL2L1ALOX5
SCHEMBL972711 0.67 CALM1 (0.69) CALM1BCL2BCL2L1ALOX5HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120184693-A1 ETHYLENE POLYMER PREPARATION METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-19 US disclosed