Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | GPR139 | Q6DWJ6 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10324159 | 1.00 | CYP1A2 (0.55) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL10323931 | 0.80 | SMN1; SMN2 (0.63) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL11297711 | 0.78 | NPC1 (0.80) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL704025 | 0.75 | TAS1R3 (0.79) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL704026 | 0.75 | TAS1R3 (0.79) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL8191196 | 0.74 | MEN1 (0.66) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL10323215 | 0.74 | MEN1 (0.66) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL5002947 | 0.74 | ALDH1A1 (0.68) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL10324474 | 0.74 | MEN1 (0.66) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL5002951 | 0.74 | ALDH1A1 (0.68) | CYP1A2CYP2C9CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120184542-A1 | PYRIDO PYRIMIDINES | ANDERSON KEVIN (US) | 2012-07-19 | — | — | US | disclosed |
| US-20120184542-A1 | PYRIDO PYRIMIDINES | ANDERSON KEVIN (US) | 2012-07-19 | — | — | US | disclosed |
| US-20120184542-A1 | PYRIDO PYRIMIDINES | ANDERSON KEVIN (US) | 2012-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184542-A1 | PYRIDO PYRIMIDINES | TYMS, TYMP, DPYD | CYP1A2 1767/4885CYP2C9 1126/4885CYP2C19 487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.