SCHEMBL10324310

SCHEMBL10324310

Cc1ccc(C(=Cc2ccc(-c3ccccc3)cc2)c2ccc([Sn](c3ccc(C(=Cc4ccc(-c5ccccc5)cc4)c4ccc(C)cc4)cc3)(c3ccc(C(=Cc4ccc(-c5ccccc5)cc4)c4ccc(C)cc4)cc3)c3ccc(C(=Cc4ccc(-c5ccccc5)cc4)c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 6/20 0.57
ESR1 P03372 2/20 0.45
ESR2 Q92731 1/20 0.41
MAPT P10636 3/20 0.40
POLB P06746 2/20 0.40
TP53 P04637 1/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
CYP19A1 P11511 1/20 0.40
CYP11B2 P19099 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10325046 1.00 PTGS2 (0.57) PTGS2ESR1ESR2MAPTPOLB
SCHEMBL10325100 0.92 ESR1 (0.52) PTGS2ESR1ESR2MAPTPOLB
SCHEMBL10324356 0.89 PTGS2 (0.62) PTGS2ESR1ESR2MAPTKDM4E
SCHEMBL10324355 0.89 PTGS2 (0.62) PTGS2ESR1ESR2MAPTKDM4E
SCHEMBL10324644 0.85 ALDH1A1 (0.46) PTGS2ESR1ESR2MAPTPOLB
SCHEMBL6288814 0.83 PTGS2 (0.62) PTGS2ESR1ESR2MAPTPOLB
SCHEMBL10325018 0.83 PTGS2 (0.41) PTGS2ESR1MAPTPOLBTP53
SCHEMBL9026538 0.82 PTGS2 (0.73) PTGS2ESR1ESR2MAPTPOLB
SCHEMBL9026535 0.82 PTGS2 (0.73) PTGS2ESR1ESR2MAPTPOLB
SCHEMBL10325064 0.81 PTGS2 (0.54) PTGS2ESR1ESR2MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012096538-A2 TIN-CENTERED DENDRIMER COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME 중앙대학교 산학협력단 (KR) 2012-07-19 WO disclosed