Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 3/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10325579 | 1.00 | LMNA (0.39) | LMNAZDHHC7DNM1SMPD1OPRM1 | |
| SCHEMBL11783887 | 0.98 | LMNA (0.36) | LMNAZDHHC7DNM1OPRM1 | |
| SCHEMBL18983091 | 0.82 | LMNA (0.46) | LMNAZDHHC7DNM1SMPD1OPRM1 | |
| SCHEMBL18983090 | 0.82 | LMNA (0.46) | LMNAZDHHC7DNM1SMPD1OPRM1 | |
| SCHEMBL28575360 | 0.82 | LMNA (0.46) | LMNAZDHHC7DNM1SMPD1OPRM1 | |
| SCHEMBL3892689 | 0.80 | LMNA (0.43) | LMNAZDHHC7OPRM1 | |
| SCHEMBL17148821 | 0.79 | LMNA (0.46) | LMNAZDHHC7DNM1SMPD1OPRM1 | |
| SCHEMBL722582 | 0.76 | PLA2G1B (0.46) | LMNAZDHHC7OPRM1SPHK1 | |
| SCHEMBL6391386 | 0.76 | GPR84 (0.46) | LMNAZDHHC7GPR84SPHK1 | |
| SCHEMBL29523549 | 0.76 | PLA2G1B (0.46) | LMNAZDHHC7OPRM1SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290522-B2 | Functionalised materials, process for the production and uses thereof | PHOSPHONICS LTD (GB) | 2016-03-22 | — | — | US | disclosed |
| US-20150105575-A1 | FUNCTIONALISED MATERIALS, PROCESS FOR THE PRODUCTION AND USES THEREOF | PHOSPHONICS LTD (GB) | 2015-04-16 | — | — | US | disclosed |
| EP-2663588-B1 | FUNCTIONALISED MATERIALS, PROCESS FOR THE PRODUCTION AND USES THEREOF | PHOSPHONICS LTD (GB) | 2014-08-20 | — | — | EP | disclosed |
| EP-2663588-A1 | FUNCTIONALISED MATERIALS, PROCESS FOR THE PRODUCTION AND USES THEREOF | Phosphonics Ltd (GB) | 2013-11-20 | — | — | EP | disclosed |
| WO-2012095307-A1 | FUNCTIONALISED MATERIALS, PROCESS FOR THE PRODUCTION AND USES THEREOF | PHOSPHONICS LTD (GB) | 2012-07-19 | — | — | WO | disclosed |