Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 7/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21671036 | 0.86 | TSHR (0.44) | TSHRALDH1A1THRBACHE | |
| SCHEMBL24354124 | 0.82 | THRB (0.50) | TSHRALDH1A1THRBACHE | |
| SCHEMBL94906 | 0.81 | TSHR (0.68) | TSHRALDH1A1THRB | |
| SCHEMBL12273875 | 0.80 | TSHR (0.41) | TSHRALDH1A1ACHEALOX15 | |
| SCHEMBL24354119 | 0.80 | TSHR (0.42) | TSHRALDH1A1THRBACHEALOX15 | |
| SCHEMBL5280138 | 0.79 | TSHR (0.49) | TSHRALDH1A1THRB | |
| SCHEMBL19998240 | 0.79 | TSHR (0.65) | TSHRALDH1A1THRB | |
| SCHEMBL275070 | 0.79 | TSHR (0.41) | TSHRALDH1A1THRBACHE | |
| SCHEMBL10325273 | 0.78 | TSHR (0.39) | TSHRALDH1A1ACHEALOX15 | |
| SCHEMBL1415848 | 0.78 | KDM4E (0.38) | ACHEALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012095293-A2 | PROCESS FOR THE SYNTHESIS OF COMPOUNDS FROM CYCLIC CARBONATES | COGNIS IP MANAGEMENT GMBH (DE) | 2012-07-19 | — | — | WO | disclosed |