Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 9/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29837289 | 0.89 | PDK2 (0.41) | GRM5PDK2P2RX7NAMPTCTDSP1 | |
| SCHEMBL13505997 | 0.87 | NAMPT (0.48) | GRM5PDK2P2RX7NAMPTCTDSP1 | |
| SCHEMBL28890054 | 0.82 | PDK2 (0.41) | PDK2P2RX7PTGDR2 | |
| SCHEMBL3239156 | 0.80 | PDK2 (0.41) | PDK2P2RX7PTGDR2 | |
| SCHEMBL19638395 | 0.80 | PDK2 (0.46) | PDK2P2RX7PTGDR2 | |
| SCHEMBL1996747 | 0.80 | ESR2 (0.46) | GRM5PDK2 | |
| SCHEMBL13506071 | 0.78 | PTGDR2 (0.41) | PDK2P2RX7PTGDR2 | |
| SCHEMBL23244374 | 0.77 | PDK2 (0.44) | PDK2P2RX7PTGDR2 | |
| SCHEMBL18446208 | 0.76 | PDK2 (0.67) | PDK2P2RX7PTGDR2 | |
| SCHEMBL25234139 | 0.75 | CPB2 (0.48) | PDK2P2RX7PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117347509-A | Purity detection method of 1-methyl-1, 4,6, 7-tetrahydro-5H-imidazo [4,5-C ] pyridine-5-carboxylic acid tert-butyl ester | 上海凌凯医药科技有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-115925702-A | Method for purifying imidazo [4,5-C ] pyridine derivative and imidazo [4,5-C ] pyridine derivative | 江西凌富生物科技有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-115605475-B | Immunosuppressant, preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-113072551-B | Nitrogen-containing biphenyl derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-112752756-B | Tetrahydro-imidazo [4,5-c ] pyridine derivatives as PD-L1 immunomodulators | 因赛特公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-115175734-B | Pyrido [3,2-D ] pyrimidine compounds as immunomodulators | 因赛特公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-117886814-A | PD-1/PD-L1 small molecule inhibitor and application thereof in medicines | 广东东阳光药业股份有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-117347509-A | Purity detection method of 1-methyl-1, 4,6, 7-tetrahydro-5H-imidazo [4,5-C ] pyridine-5-carboxylic acid tert-butyl ester | 上海凌凯医药科技有限公司 | 2024-01-05 | — | — | CN | disclosed |
| EP-4286383-A1 | BIPHENYL COMPOUND AS IMMUNOMODULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | Shenzhen Chipscreen Biosciences Co., Ltd. (CN) | 2023-12-06 | — | — | EP | disclosed |
| EP-4223369-A1 | IMMUNOMODULATOR COMPOUNDS AND METHODS OF USE | Incyte Corporation (US) | 2023-08-09 | — | — | EP | disclosed |
| CN-114502556-B | Biphenyl fluoro double bond derivative, preparation method thereof and application thereof in pharmacy | 上海和誉生物医药科技有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-115611924-A | PD-1/PD-L1 inhibitor and preparation method and application thereof | 上海华汇拓医药科技有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-115605475-A | Immunosuppressant, preparation method and application thereof | 上海和誉生物医药科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-112812113-B | Immunomodulatory compounds, compositions and uses thereof | 杭州和正医药有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-114829366-A | Salts and crystalline forms of PD-1/PD-L1 inhibitors | 因赛特公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114502556-A | Biphenyl fluoro double bond derivative and preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2022089511-A1 | BIPHENYL COMPOUND AS IMMUNOMODULATOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳微芯生物科技股份有限公司 | 2022-05-05 | — | — | WO | disclosed |
| EP-3558963-B1 | BICYCLIC HETEROAROMATIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORP (US) | 2022-03-23 | — | — | EP | disclosed |
| CN-111925367-A | Fused ring derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2020-11-13 | — | — | CN | disclosed |
| WO-2012097062-A1 | METHODS FOR TREATING OR PREVENTING CARDIAC AND NEUROLOGICAL DISORDERS USING CHEMOKINE RECEPTOR ANTAGONISTS | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-07-19 | — | — | WO | disclosed |