Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10325665 | 0.80 | GRM5 (0.44) | PDK2P2RX7PTGDR2 | |
| SCHEMBL28890054 | 0.78 | PDK2 (0.41) | PDK2P2RX7PTGDR2 | |
| SCHEMBL19638395 | 0.77 | PDK2 (0.46) | PDK2P2RX7PTGDR2 | |
| SCHEMBL29837289 | 0.77 | PDK2 (0.41) | PDK2P2RX7PTGDR2 | |
| SCHEMBL20793348 | 0.76 | HRH3 (0.33) | — | |
| SCHEMBL23244374 | 0.73 | PDK2 (0.44) | PDK2P2RX7PTGDR2 | |
| SCHEMBL20818245 | 0.73 | PDK2 (0.35) | PDK2P2RX7 | |
| SCHEMBL18446208 | 0.72 | PDK2 (0.67) | PDK2P2RX7PTGDR2 | |
| SCHEMBL25234139 | 0.71 | CPB2 (0.48) | PDK2P2RX7PTGDR2 | |
| SCHEMBL13506071 | 0.71 | PTGDR2 (0.41) | PDK2P2RX7PTGDR2CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010031789-A1 | NEW COMPOUNDS I | BIOVITRUM AB (PUBL) (SE) | 2010-03-25 | — | — | WO | disclosed |