Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 8/20 | 0.71 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.71 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.71 |
| ▸ | MRGPRX2 | Q96LB1 | 4/20 | 0.71 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.71 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.71 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.71 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.64 |
| ▸ | ARRB1 | P49407 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8370691 | 0.91 | MRGPRX2 (0.71) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Morphine 3-Glucuronide SCHEMBL3843209 | 0.89 | MRGPRX2 (0.74) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Morphine 3-Glucuronide SCHEMBL614298 | 0.89 | MRGPRX2 (0.74) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Codeine SCHEMBL8218174 | 0.84 | OPRD1 (1.00) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Codeine SCHEMBL14371354 | 0.84 | OPRD1 (1.00) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Codeine SCHEMBL1560699 | 0.84 | OPRD1 (1.00) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Codeine SCHEMBL13696342 | 0.84 | OPRD1 (1.00) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Codeine SCHEMBL10329428 | 0.84 | OPRD1 (1.00) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Codeine SCHEMBL21077535 | 0.84 | OPRD1 (1.00) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Codeine SCHEMBL3257 | 0.84 | OPRD1 (1.00) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3740115-B1 | A BIOASSAY FOR THE NON-INVASIVE DETECTION OF DRUG USE AND PHYSIOLOGIC CONDITIONS | CHILDRENS NAT MEDICAL CT (US) | 2025-08-27 | — | — | EP | claimed |
| EP-1912658-B1 | THERAPEUTIC PROTOCOLS USING HYALURONAN | ALCHEMIA ONCOLOGY PTY LTD (AU) | 2017-01-25 | — | — | EP | claimed |
| EP-2301526-B1 | Morphine controlled release system | EGALET LTD (GB) | 2016-03-23 | — | — | EP | claimed |
| EP-1610767-B1 | MORPHINE CONTROLLED RELEASE SYSTEM | EGALET AS (DK) | 2011-01-19 | — | — | EP | claimed |
| EP-0496839-B2 | VACCINE AGAINST DRUGS OF ABUSE | CHILKA LTD (VG) | 2004-03-03 | — | — | EP | disclosed |
| EP-1183023-A1 | USE OF VERAPAMIL AND VERAPAMIL DERIVATIVES FOR PRODUCING MEDICAMENTS WITH AN INHIBITING EFFECT ON BETA-GLUCURONIDASE IN HUMAN TISSUE | PAZ ARZNEIMITTEL- ENTWICKLUNGSGESELLSCHAFT MBH (DE) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000074670-A1 | USE OF VERAPAMIL AND VERAPAMIL DERIVATIVES FOR PRODUCING MEDICAMENTS WITH AN INHIBITING EFFECT ON β-GLUCURONIDASE IN HUMAN TISSUE | PAZ ARZNEIMITTEL-ENTWICKLUNGS GESELLSCHAFT MBH (DE) | 2000-12-14 | — | — | WO | disclosed |
| EP-0496839-B1 | VACCINE AGAINST DRUGS OF ABUSE | BIO DEV LTD (IR) | 1996-05-15 | — | — | EP | disclosed |
| EP-0496839-A1 | VACCINE AND IMMUNOSERUM AGAINST DRUGS OF ABUSE. | CERNY ERICH H (CH) | 1992-08-05 | — | — | EP | disclosed |
| WO-1992003163-A1 | VACCINE AND IMMUNOSERUM AGAINST DRUGS OF ABUSE | CERNY ERICH H (CH) | 1992-03-05 | — | — | WO | disclosed |