Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9579235 | 0.76 | RIPK1 (0.42) | CYP2D6CYP1A2KCNN4CYP2C19HIF1A | |
| SCHEMBL6284917 | 0.76 | GRIN1 (0.44) | CYP2D6CYP1A2KCNN4CYP2C19HIF1A | |
| SCHEMBL16160264 | 0.74 | KCNN4 (0.40) | CYP2D6CYP1A2KCNN4CYP2C19HIF1A | |
| SCHEMBL11741048 | 0.74 | CYP2C19 (0.42) | CYP2D6CYP1A2KCNN4CYP2C19HIF1A | |
| SCHEMBL24243940 | 0.73 | KCNN4 (0.39) | CYP2D6CYP1A2KCNN4CYP2C19HIF1A | |
| SCHEMBL12238644 | 0.73 | CYP2C19 (0.44) | CYP2D6CYP1A2KCNN4CYP2C19HIF1A | |
| SCHEMBL19954704 | 0.73 | CYP2D6 (0.43) | CYP2D6CYP1A2KCNN4CYP2C19HIF1A | |
| SCHEMBL147712 | 0.72 | KCNN4 (0.52) | CYP2D6CYP1A2KCNN4ALDH1A1TAAR1 | |
| SCHEMBL10808021 | 0.72 | CYP2C19 (0.54) | KCNN4CYP2C19HIF1AALDH1A1TAAR1 | |
| SCHEMBL599044 | 0.72 | CYP2C19 (0.54) | KCNN4CYP2C19HIF1AALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2663594-B1 | ANTIOXIDANT COMPOUNDS FOR POLYOLEFIN RESINS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-12-26 | — | — | EP | claimed |
| CN-103415564-B | For the anti-oxidant compounds of polyolefin resin | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-04-13 | — | — | CN | claimed |
| EP-2663594-A1 | ANTIOXIDANT COMPOUNDS FOR POLYOLEFIN RESINS | Dow Global Technologies LLC (US) | 2013-11-20 | — | — | EP | claimed |
| US-20130287985-A1 | ANTIOXIDANT COMPOUNDS FOR POLYOLEFIN RESINS | DEMIRORS MEHMET (US) | 2013-10-31 | — | — | US | claimed |
| WO-2012096962-A1 | ANTIOXIDANT COMPOUNDS FOR POLYOLEFIN RESINS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-07-19 | — | — | WO | claimed |
| EP-2663594-B1 | ANTIOXIDANT COMPOUNDS FOR POLYOLEFIN RESINS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-12-26 | — | — | EP | disclosed |
| CN-103415564-B | For the anti-oxidant compounds of polyolefin resin | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-04-13 | — | — | CN | disclosed |
| EP-2663594-A1 | ANTIOXIDANT COMPOUNDS FOR POLYOLEFIN RESINS | Dow Global Technologies LLC (US) | 2013-11-20 | — | — | EP | disclosed |
| US-20130287985-A1 | ANTIOXIDANT COMPOUNDS FOR POLYOLEFIN RESINS | DEMIRORS MEHMET (US) | 2013-10-31 | — | — | US | disclosed |
| WO-2012096962-A1 | ANTIOXIDANT COMPOUNDS FOR POLYOLEFIN RESINS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-07-19 | — | — | WO | disclosed |