SCHEMBL6284917

SCHEMBL6284917

CCC(c1ccccc1)(c1ccccc1)C(C)C

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GRIN1 Q05586 5/20 0.44
GRIN2A Q12879 5/20 0.44
GRIN2D O15399 4/20 0.44
GRIN2C Q14957 4/20 0.44
GRIN2B Q13224 3/20 0.44
KCNN4 O15554 1/20 0.41
CYP2D6 P10635 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 2/20 0.39
HIF1A Q16665 1/20 0.39
ALDH1A1 P00352 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
RIPK1 Q13546 1/20 0.38
KCNH2 Q12809 1/20 0.37
KIF11 P52732 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20381846 0.88 KIF11 (0.42) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL12809670 0.82 GRIN1 (0.42) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL15563080 0.82 GRIN1 (0.42) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL4454908 0.79 GRIN1 (0.43) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL11988595 0.79 RIPK1 (0.41) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL416118 0.79 GRIN1 (0.47) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL15562534 0.79 KIF11 (0.42) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL17042318 0.77 ESR1 (0.56) CYP2D6CYP1A2CYP2C19ALDH1A1HSD17B10
SCHEMBL1058675 0.77 LMNA (0.40) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL1058678 0.77 LMNA (0.40) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6967229-B2 Carbon-carbon initiators for use in golf balls ACUSHNET COMPANY (US) 2005-11-22 US claimed
US-20050009992-A1 Carbon-carbon initiators for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US claimed
EP-3131965-A1 METHODS OF PREPARING COMPOSITIONS FOR CONTAINERS AND OTHER ARTICLES AND METHODS OF USING SAME Valspar Sourcing, Inc. (US) 2017-02-22 EP disclosed
WO-2015160788-A1 METHODS OF PREPARING COMPOSITIONS FOR CONTAINERS AND OTHER ARTICLES AND METHODS OF USING SAME VALSPAR SOURCING, INC. (US) 2015-10-22 WO disclosed
EP-2882792-A1 POLYCARBONATES Valspar Sourcing, Inc. (US) 2015-06-17 EP disclosed
EP-2882401-A1 DENTAL MATERIALS AND METHOD OF MANUFACTURE Valspar Sourcing, Inc. (US) 2015-06-17 EP disclosed
EP-2883113-A1 DEVELOPER FOR THERMALLY RESPONSIVE RECORD MATERIALS Valspar Sourcing, Inc. (US) 2015-06-17 EP disclosed
EP-2882818-A1 STABILIZER AND COATING COMPOSITIONS THEREOF Valspar Sourcing, Inc. (US) 2015-06-17 EP disclosed
EP-2882658-A1 CONTAINER COATING SYSTEM Valspar Sourcing, Inc. (US) 2015-06-17 EP disclosed
US-9056227-B2 Golf ball comprising a core having a shallow hardness gradient ACUSHNET COMPANY (US) 2015-06-16 US disclosed
US-8968117-B2 Dual-core comprising zero gradient center and positive gradient outer core layer ACUSHNET COMPANY (US) 2015-03-03 US disclosed
US-20130109504-A1 DUAL-CORE COMPRISING ZERO GRADIENT CENTER AND POSITIVE GRADIENT OUTER CORE LAYER ACUSHNET COMPANY (US) 2013-05-02 US disclosed
CN-1290905-C Cyst plate extruded from polystyrene resin and the manufacturing process thereof JSP K K (JP) 2006-12-20 CN disclosed
US-6967229-B2 Carbon-carbon initiators for use in golf balls ACUSHNET COMPANY (US) 2005-11-22 US disclosed
US-20050009992-A1 Carbon-carbon initiators for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US disclosed
CN-1482162-A Cyst plate extruded from polystyrene resin and the manufacturing process thereof 株式会社JSP 2004-03-17 CN disclosed
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed