Bicarbonate

Bicarbonate

SCHEMBL10325879

C=CC(F)C=C.O=C(O)O

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
TSHR P16473 2/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
BLM P54132 1/20 0.33
SLC6A3 Q01959 1/20 0.33
MEN1 O00255 1/20 0.33
CYP2D6 P10635 1/20 0.33
NFKB1 P19838 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 2/20 0.30
FGFR4 P22455 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL698070 0.83
SCHEMBL235177 0.82
Bicarbonate SCHEMBL28629341 0.81 LMNA (0.30) LMNA
Bicarbonate SCHEMBL17581395 0.78
Bicarbonate SCHEMBL16105730 0.75 LMNA (0.35) LMNATSHRSLC6A2SLC6A4BLM
SCHEMBL2592931 0.75
SCHEMBL9722524 0.73 GABRR1 (0.34)
Bicarbonate SCHEMBL6361730 0.72
Bicarbonate SCHEMBL17581397 0.71 LMNA (0.32) LMNA
SCHEMBL1736176 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117154222-A Secondary battery and electric device 浙江锂威能源科技有限公司 2023-12-01 CN disclosed
WO-2022047628-A1 ELECTROLYTE SOLUTION, ELECTROCHEMICAL DEVICE AND ELECTRONIC DEVICE 宁德新能源科技有限公司 2022-03-10 WO disclosed
CN-113273011-A Electrolyte solution, electrochemical device, and electronic device 宁德新能源科技有限公司 2021-08-17 CN disclosed
US-9070951-B2 Solvent for nonaqueous electrolyte solution of lithium secondary battery DAIKIN INDUSTRIES, LTD. (JP) 2015-06-30 US disclosed
US-20120183867-A1 SOLVENT FOR NONAQUEOUS ELECTROLYTE SOLUTION OF LITHIUM SECONDARY BATTERY DAIKIN INDUSTRIES, LTD. (JP) 2012-07-19 US disclosed