Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | F12 | P00748 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1222203 | 0.91 | CYP1A2 (0.36) | SMN1; SMN2TDP1KDM4EALDH1A1MAPT | |
| SCHEMBL1221729 | 0.87 | CYP1A2 (0.36) | SMN1; SMN2TDP1KDM4EALDH1A1MAPT | |
| SCHEMBL1222312 | 0.87 | PARP1 (0.32) | GAAOPRK1CCR6SMN1; SMN2NPSR1 | |
| SCHEMBL15334697 | 0.84 | PARP1 (0.35) | ALDH1A1KMT2APARP1PAK1 | |
| SCHEMBL1221366 | 0.84 | PIK3CD (0.37) | ALDH1A1KMT2APARP1PAK1 | |
| SCHEMBL13512876 | 0.83 | PARP1 (0.36) | KMT2APARP1PAK1 | |
| SCHEMBL13512875 | 0.81 | LMNA (0.33) | ALDH1A1KMT2A | |
| SCHEMBL12894145 | 0.81 | CYP1A2 (0.34) | SMN1; SMN2TDP1KDM4EALDH1A1MAPT | |
| SCHEMBL1222138 | 0.80 | CASP1 (0.35) | SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL14749231 | 0.80 | NPC1 (0.31) | GAACCR6SMN1; SMN2PAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012095388-A2 | COMPOUNDS FOR TREATMENT OF FELINE LEUKEMIA IN FELIDAE | Universität Zürich (CH) | 2012-07-19 | — | — | WO | claimed |
| WO-2012095388-A2 | COMPOUNDS FOR TREATMENT OF FELINE LEUKEMIA IN FELIDAE | Universität Zürich (CH) | 2012-07-19 | — | — | WO | disclosed |
| WO-2012095388-A2 | COMPOUNDS FOR TREATMENT OF FELINE LEUKEMIA IN FELIDAE | Universität Zürich (CH) | 2012-07-19 | — | — | WO | disclosed |