Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 2/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | SQSTM1 | Q13501 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4240174 | 0.99 | LMNA (0.39) | LMNATSHRHTTSMN1; SMN2KIT | |
| SCHEMBL1030310 | 0.90 | TSHR (0.41) | LMNATSHRHTTSMN1; SMN2ST14 | |
| Hydrochloric Acid SCHEMBL4246986 | 0.89 | TSHR (0.40) | LMNATSHRHTTSMN1; SMN2ST14 | |
| SCHEMBL1029498 | 0.89 | KIT (0.41) | LMNATSHRHTTSMN1; SMN2KIT | |
| SCHEMBL1032791 | 0.88 | TSHR (0.44) | LMNATSHRHTTSMN1; SMN2ST14 | |
| Hydrochloric Acid SCHEMBL4243947 | 0.88 | KIT (0.41) | LMNATSHRHTTSMN1; SMN2KIT | |
| SCHEMBL1031476 | 0.87 | FFAR4 (0.40) | LMNATSHRHTTSMN1; SMN2ST14 | |
| Hydrochloric Acid SCHEMBL4245486 | 0.87 | TSHR (0.44) | LMNATSHRHTTSMN1; SMN2ST14 | |
| SCHEMBL1031793 | 0.86 | LMNA (0.35) | LMNATSHRHTTSMN1; SMN2ST14 | |
| SCHEMBL1027217 | 0.86 | LMNA (0.35) | LMNATSHRHTTSMN1; SMN2ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013179-B1 | ARYLOXYETHYLAMINE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR | ABBOTT GMBH & CO KG (DE) | 2011-01-19 | — | — | EP | disclosed |