Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 15/20 | 0.65 |
| ▸ | PDGFRA | P16234 | 12/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KIT | P10721 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1029982 | 0.86 | PDGFRB (0.61) | PDGFRBPDGFRAGAAMAPTKIT | |
| SCHEMBL1032705 | 0.86 | PDGFRB (0.62) | PDGFRBPDGFRAGAAMAPTKIT | |
| SCHEMBL1028115 | 0.80 | KIT (0.66) | PDGFRBPDGFRAGAAMAPTKIT | |
| Hydrochloric Acid SCHEMBL1031469 | 0.79 | PDGFRB (0.61) | PDGFRBPDGFRAMAPTKITKDM4E | |
| SCHEMBL2923035 | 0.78 | PDGFRB (1.00) | PDGFRBPDGFRAKITKDRFLT3 | |
| SCHEMBL1792762 | 0.78 | MAPT (0.67) | GAAMAPT | |
| SCHEMBL7664440 | 0.75 | MEN1 (0.53) | PDGFRBPDGFRAGAAMAPTKIT | |
| SCHEMBL2914254 | 0.74 | PDGFRB (0.78) | PDGFRBPDGFRAKIT | |
| SCHEMBL1029983 | 0.72 | RECQL (0.62) | PDGFRBPDGFRAGAAMAPTKIT | |
| SCHEMBL1002967 | 0.71 | AKT2 (0.54) | MAPTKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067123-B1 | NITROGENOUS HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KIRIN CO LTD (JP) | 2011-01-19 | — | — | EP | disclosed |
| US-6423716-B1 | Nitrogenous heterocyclic compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-07-23 | — | — | US | disclosed |
| EP-1067123-A1 | NITROGENOUS HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-01-10 | — | — | EP | disclosed |