Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6469380 | 0.85 | OPRM1 (0.59) | OPRM1OPRL1CARM1PRMT6SIGMAR1 | |
| SCHEMBL25011406 | 0.84 | CTSL (0.46) | OPRM1OPRL1CARM1PRMT6SIGMAR1 | |
| SCHEMBL26581191 | 0.83 | CARM1 (0.40) | OPRM1OPRL1CARM1PRMT6SIGMAR1 | |
| SCHEMBL18361624 | 0.82 | OPRM1 (0.57) | OPRM1OPRL1CARM1PRMT6SIGMAR1 | |
| SCHEMBL25741005 | 0.81 | OPRM1 (0.43) | OPRM1OPRL1CARM1PRMT6SIGMAR1 | |
| SCHEMBL2668584 | 0.80 | OPRM1 (0.55) | OPRM1OPRL1CARM1PRMT6SIGMAR1 | |
| SCHEMBL17112355 | 0.80 | OPRM1 (0.55) | OPRM1OPRL1CARM1PRMT6SIGMAR1 | |
| SCHEMBL10052775 | 0.80 | OPRM1 (0.55) | OPRM1OPRL1CARM1PRMT6SIGMAR1 | |
| SCHEMBL15797812 | 0.80 | OPRM1 (0.54) | OPRM1OPRL1CARM1PRMT6SIGMAR1 | |
| SCHEMBL6108529 | 0.80 | OPRM1 (0.54) | OPRM1OPRL1CARM1PRMT6SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11826351-B2 | Compounds useful as kinase inhibitors | LOXO ONCOLOGY INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-20230372298-A1 | COMPOUNDS USEFUL AS KINASE INHIBITORS | LOXO ONCOLOGY, INC. | 2023-11-23 | — | — | US | disclosed |
| US-20230116972-A1 | CD38 MODULATORS AND METHODS OF USE THEREOF | CYTOKINETICS, INC. | 2023-04-20 | — | — | US | disclosed |
| US-8791303-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2014-07-29 | — | — | US | disclosed |
| US-8791303-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2014-07-29 | — | — | US | disclosed |
| US-20120178623-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230116972-A1 | CD38 MODULATORS AND METHODS OF USE THEREOF | CD38, CXCR4, FCGRT | OPRM1 626/4885OPRL1 1004/4885CARM1 1061/4885 |
| US-11826351-B2 | Compounds useful as kinase inhibitors | BTK, ABL1, LCK | OPRM1 4852/4885OPRL1 3242/4885CARM1 1675/4885 |
| US-20120178623-A1 | NOVEL HERBICIDES | DDT, CBR3, C9 | OPRM1 872/4885OPRL1 1215/4885CARM1 1495/4885 |
| US-20230372298-A1 | COMPOUNDS USEFUL AS KINASE INHIBITORS | BTK, ABL1, LCK | OPRM1 4852/4885OPRL1 3242/4885CARM1 1675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.