Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1032310 | 0.83 | ADORA2A (0.42) | KMT2ACYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL1029856 | 0.81 | HTT (0.46) | KMT2ACYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL1030837 | 0.81 | NPC1 (0.44) | KMT2AMEN1KDM4EHPGDPOLB | |
| SCHEMBL1031730 | 0.80 | CNR1 (0.45) | KMT2ACYP2C9CYP2C19MEN1KDM4E | |
| SCHEMBL1031988 | 0.79 | CNR1 (0.44) | KMT2ACYP2C9CYP2C19MEN1KDM4E | |
| SCHEMBL1032145 | 0.79 | EPHX2 (0.45) | — | |
| SCHEMBL1030813 | 0.77 | TSHR (0.46) | KMT2ACYP2C9CYP2C19MEN1POLB | |
| SCHEMBL1031836 | 0.77 | MEN1 (0.43) | KMT2ACYP2C9MEN1POLBLMNA | |
| SCHEMBL1031640 | 0.76 | ALDH1A1 (0.52) | KMT2ACYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL1031499 | 0.76 | SMN1; SMN2 (0.41) | KMT2ACYP2C19KDM4EHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035375-B1 | 1,3-DISUBSTITUTED 4-METHYL-1H-PYRROLE-2-CARBOXAMIDES AND THEIR USE FOR THE MANUFACTURE OF MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2011-01-19 | — | — | EP | claimed |