SCHEMBL1032826

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1033396	0.94	HDAC4 (0.46)	POLBMEN1KMT2ADRD4MAP4K4
	SCHEMBL1033395	0.94	HDAC4 (0.46)	POLBMEN1KMT2ADRD4MAP4K4
	SCHEMBL1035236	0.91	MAPT (0.50)	POLBMEN1KMT2ADRD4MAP4K4
	SCHEMBL1034071	0.88	CNR2 (0.49)	POLBDRD4MAP4K4PARP1KDM1A
	SCHEMBL17772313	0.82	DRD4 (0.46)	DRD4MAP4K4KDM1AMAOAMAOB
	SCHEMBL12673385	0.82	PARP1 (0.63)	CASP6PARP1PBK
	SCHEMBL13626995	0.81	DRD4 (0.47)	MEN1KMT2ADRD4MAP4K4KDM1A
	SCHEMBL12880950	0.81	PARP1 (0.50)	POLBMEN1KMT2ADRD4PARP1
	SCHEMBL1034785	0.81	SCN7A (0.42)	DRD4MAP4K4PARP1KDM1ASCN9A
	SCHEMBL1034477	0.81	RXFP1 (0.44)	GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.