SCHEMBL103283

SCHEMBL103283

CN1CCC(O)(CN)CC1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.36
GAA P10253 2/20 0.36
RAD52 P43351 1/20 0.36
NCF1 P14598 1/20 0.36
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
SLC6A3 Q01959 2/20 0.33
CYP1A2 P05177 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
BDKRB2 P30411 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL14311936 0.98 KMT2A (0.35) KMT2AGAARAD52NCF1SLC6A2
Hydrochloric Acid SCHEMBL7401430 0.98 KMT2A (0.35) KMT2AGAARAD52NCF1SLC6A2
Hydrochloric Acid SCHEMBL9030273 0.95 NPSR1 (0.34) KMT2AGAARAD52NCF1SLC6A2
SCHEMBL20007916 0.91 KMT2A (0.33) KMT2AGAARAD52NCF1SLC6A2
Acetic Acid SCHEMBL10639731 0.91 CYP1A2 (0.37) KMT2AGAARAD52SLC6A2SLC6A4
SCHEMBL16295697 0.86
SCHEMBL8589603 0.82 NPSR1 (0.36) SLC6A2SLC6A3CYP1A2NPSR1MAPK1
SCHEMBL383477 0.81 NCF1 (0.33) KMT2AGAARAD52NCF1CYP1A2
SCHEMBL8372902 0.77 KMT2A (0.34) KMT2AGAASLC6A4NPSR1MAPK1
SCHEMBL3436780 0.77 NPSR1 (0.33) KMT2AGAANPSR1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114507184-B Synthesis method and application of 1-methyl hexahydroazepin-4-one hydrochloride 好医生药业集团有限公司 2024-02-13 CN claimed
CN-114507184-A Synthesis method and application of 1-methylhexahydroazepin-4-one hydrochloride 好医生药业集团有限公司 2022-05-17 CN claimed
US-20250320217-A1 SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES AS PROTEIN KINASE INHIBITORS SUMITOMO PHARMA AMERICA INC (US) 2025-10-16 US disclosed
US-12398097-B2 WDR5-MYC inhibitors VANDERBILT UNIVERSITY (US) 2025-08-26 US disclosed
US-20250129085-A1 SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES AS PROTEIN KINASE INHIBITORS SUMITOMO PHARMA AMERICA INC (US) 2025-04-24 US disclosed
CN-114507184-B Synthesis method and application of 1-methyl hexahydroazepin-4-one hydrochloride 好医生药业集团有限公司 2024-02-13 CN disclosed
CN-114507184-B Synthesis method and application of 1-methyl hexahydroazepin-4-one hydrochloride 好医生药业集团有限公司 2024-02-13 CN disclosed
CN-111936496-B Heterocyclic compounds useful as medicaments 马萨里克大学 2023-12-29 CN disclosed
US-11746091-B2 Cannabinoid receptor modulators ARENA PHARMACEUTICALS, INC. (US) 2023-09-05 US disclosed
EP-3515916-B1 SHP2 PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF RELAY THERAPEUTICS INC (US) 2023-06-07 EP disclosed
EP-3867238-B1 PROTEIN TYROSINE PHOSPHATASE INHIBITORS ARRAY BIOPHARMA INC (US) 2023-06-07 EP disclosed
CN-1129942-A Aza spiro-compounds acting on the cholinergic system with muscarinic agonist activity ISRAEL INST BIOLOG RES (IL) 1996-08-28 CN disclosed
US-5534520-A Spiro compounds containing five-membered rings ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) 1996-07-09 US disclosed
EP-0711292-A1 AZA SPIRO COMPOUNDS ACTING ON THE CHOLINERGIC SYSTEM WITH MUSCARINIC AGONIST ACTIVITY KOSMIN, Gerald, Emmanuel (GB) 1996-05-15 EP disclosed
US-5407938-A Treating central nervous system disorders; Alzheimer*s ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) 1995-04-18 US disclosed
WO-1995003303-A2 AZA SPIRO COMPOUNDS ACTING ON THE CHOLINERGIC SYSTEM WITH MUSCARINIC AGONIST ACTIVITY STATE OF ISRAEL, REPRESENTED BY THE PRIME MINISTER'S OFFICE, ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) 1995-02-02 WO disclosed
EP-0452101-A2 Spiro bridged and unbridged heterocyclic compounds ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) 1991-10-16 EP disclosed
EP-0343307-A1 4-Piperidinealkanamine derivatives FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (ES) 1989-11-29 EP disclosed
EP-0295833-A1 Aromatic-Spiropiperidine oxazepinones (and thiones) A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) 1988-12-21 EP disclosed
US-4746655-A ANTIHISTAMINES A. H. ROBINS COMPANY, INCORPORATED (US) 1988-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129085-A1 SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES AS PROTEIN KINASE INHIBITORS PIM1, PIM2, PIM3 KMT2A 1046/4885GAA 4532/4885RAD52 3023/4885
US-11746091-B2 Cannabinoid receptor modulators CNR1, CNR2, TRPV1 KMT2A 2962/4885GAA 3665/4885RAD52 3678/4885
US-20250320217-A1 SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES AS PROTEIN KINASE INHIBITORS PIM1, PIM2, PIM3 KMT2A 1046/4885GAA 4532/4885RAD52 3023/4885
US-12398097-B2 WDR5-MYC inhibitors MYC, WDR5, MYCBP KMT2A 186/4885GAA 3730/4885RAD52 2043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.