Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7640960 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2CA14ALDH1A1KMT2ACA12 | |
| SCHEMBL29064781 | 0.88 | — | — | |
| SCHEMBL10329475 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2CA14ALDH1A1KMT2ACA12 | |
| SCHEMBL2138019 | 0.85 | — | — | |
| SCHEMBL8313441 | 0.81 | SMN1; SMN2 (0.34) | SMN1; SMN2CA14ALDH1A1 | |
| SCHEMBL5755090 | 0.80 | — | — | |
| SCHEMBL2035273 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2CA14ALDH1A1KMT2ACA12 | |
| SCHEMBL14574445 | 0.79 | SMN1; SMN2 (0.39) | SMN1; SMN2CA14ALDH1A1KMT2ACA12 | |
| SCHEMBL11574487 | 0.79 | SMN1; SMN2 (0.37) | SMN1; SMN2CA14KMT2ACA12 | |
| SCHEMBL932508 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104211679-B | 1,3-dithiolane derivatives, synthesis, nano structure, activity, and application thereof as lead dispelling agent | 首都医科大学 | 2017-05-24 | — | — | CN | claimed |
| CN-104211679-A | 1,3-dithiolane derivatives, synthesis, nano structure, activity, and application thereof as lead dispelling agent | UNIV CAPITAL MEDICAL SCIENCES | 2014-12-17 | — | — | CN | claimed |
| CN-102241665-B | 4-(4,5-dimethoxycarboxyl-1,3-dithiolane-2-yl)benzoyl-L-amino acid benzyl ester as well as synthesis method and applications thereof | UNIV CAPITAL MEDICAL | 2013-05-08 | — | — | CN | claimed |
| CN-102241665-A | 4-(4,5-dimethoxycarboxyl-1,3-dithiolane-2-yl)benzoyl-L-amino acid benzyl ester as well as synthesis method and applications thereof | UNIV CAPITAL MEDICAL | 2011-11-16 | — | — | CN | claimed |
| US-20180161261-A1 | METHOD FOR DECOLORIZING DYED KERATINIC FIBERS | HENKEL AG & CO. KGAA (DE) | 2018-06-14 | — | — | US | disclosed |
| CN-104211679-B | 1,3-dithiolane derivatives, synthesis, nano structure, activity, and application thereof as lead dispelling agent | 首都医科大学 | 2017-05-24 | — | — | CN | disclosed |
| CN-104211679-A | 1,3-dithiolane derivatives, synthesis, nano structure, activity, and application thereof as lead dispelling agent | UNIV CAPITAL MEDICAL SCIENCES | 2014-12-17 | — | — | CN | disclosed |
| CN-102241665-B | 4-(4,5-dimethoxycarboxyl-1,3-dithiolane-2-yl)benzoyl-L-amino acid benzyl ester as well as synthesis method and applications thereof | UNIV CAPITAL MEDICAL | 2013-05-08 | — | — | CN | disclosed |
| EP-2300518-B1 | ANTIREFLECTIVE COATING COMPOSITIONS | AZ ELECTRONIC MATERIALS USA (US) | 2012-08-15 | — | — | EP | disclosed |
| US-8221965-B2 | Antireflective coating compositions | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2012-07-17 | — | — | US | disclosed |
| US-8221965-B2 | Antireflective coating compositions | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2012-07-17 | — | — | US | disclosed |
| CN-102241665-A | 4-(4,5-dimethoxycarboxyl-1,3-dithiolane-2-yl)benzoyl-L-amino acid benzyl ester as well as synthesis method and applications thereof | UNIV CAPITAL MEDICAL | 2011-11-16 | — | — | CN | disclosed |
| US-20100009293-A1 | Antireflective Coating Compositions | MERCK PATENT GMBH (DE) | 2010-01-14 | — | — | US | disclosed |
| US-20100009293-A1 | Antireflective Coating Compositions | MERCK PATENT GMBH (DE) | 2010-01-14 | — | — | US | disclosed |
| WO-2010004377-A1 | ANTIREFLECTIVE COATING COMPOSITIONS | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2010-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180161261-A1 | METHOD FOR DECOLORIZING DYED KERATINIC FIBERS | KRT18, DUOX2, AOC1 | SMN1; SMN2 4570/4885CA14 561/4885ALDH1A1 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.