⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3434601 | 0.69 | — | — | |
| SCHEMBL15761278 | 0.69 | — | — | |
| SCHEMBL4346880 | 0.67 | — | — | |
| SCHEMBL13211003 | 0.67 | — | — | |
| SCHEMBL28303423 | 0.67 | — | — | |
| SCHEMBL23424079 | 0.67 | ALDH1A1 (0.31) | — | |
| SCHEMBL14220213 | 0.65 | — | — | |
| SCHEMBL16286199 | 0.65 | ALDH1A1 (0.40) | — | |
| SCHEMBL11186861 | 0.63 | — | — | |
| SCHEMBL19120013 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2476689-A1 | Thiocarbon-protecting groups for RNA synthesis | Agilent Technologies, Inc. (US) | 2012-07-18 | — | — | EP | disclosed |
| WO-2008141248-A2 | THIOCARBON-PROTECTING GROUPS FOR RNA SYNTHESIS | AGILENT TECHNOLOGIES, INC. (US) | 2008-11-20 | — | — | WO | disclosed |