SCHEMBL10330375

SCHEMBL10330375

COCCOc1ccc2nc(-c3ccccc3)c(-c3ccccc3)nc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.54
KDM4E B2RXH2 9/20 0.54
L3MBTL1 Q9Y468 5/20 0.54
LMNA P02545 4/20 0.54
NPSR1 Q6W5P4 2/20 0.54
TDP1 Q9NUW8 1/20 0.54
KMT2A Q03164 3/20 0.54
MEN1 O00255 2/20 0.54
MAPT P10636 1/20 0.54
GPR55 Q9Y2T6 1/20 0.54
POLB P06746 2/20 0.51
ATM Q13315 1/20 0.47
TLR9 Q9NR96 1/20 0.47
MAPK1 P28482 1/20 0.47
RECQL P46063 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
TP53 P04637 1/20 0.46
GAA P10253 3/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14304819 0.85 ALDH1A1 (0.56) ALDH1A1KDM4EL3MBTL1LMNANPSR1
SCHEMBL23063657 0.82 PIK3CG (0.50) ALDH1A1KDM4ELMNATDP1KMT2A
SCHEMBL8112450 0.81 KDM4E (0.74) ALDH1A1KDM4EL3MBTL1LMNANPSR1
SCHEMBL31070199 0.81 KDM4E (0.74) ALDH1A1KDM4EL3MBTL1LMNANPSR1
SCHEMBL10330377 0.81 ALDH1A1 (0.49) ALDH1A1KDM4EL3MBTL1LMNANPSR1
SCHEMBL23063656 0.79 TSHR (0.43) ALDH1A1LMNAKMT2AMEN1MAPK1
SCHEMBL23063651 0.79 ALDH1A1 (0.45) ALDH1A1KDM4EL3MBTL1LMNANPSR1
SCHEMBL21642369 0.78 PDE2A (0.46) ALDH1A1KDM4ELMNAKMT2AMEN1
SCHEMBL11242184 0.75 ALDH1A1 (0.49) ALDH1A1KDM4EL3MBTL1LMNATDP1
SCHEMBL14076263 0.73 ALDH1A1 (0.73) ALDH1A1KDM4EL3MBTL1LMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2041200-B1 NOVEL ELECTROLUMINESCENT POLYMERS FOR ELECTRONIC APPLICATIONS UDC IRELAND LTD (IE) 2018-03-07 EP disclosed
US-8221906-B2 Electroluminescent polymers for electronic applications BASF SE (DE) 2012-07-17 US disclosed
US-8221906-B2 Electroluminescent polymers for electronic applications BASF SE (DE) 2012-07-17 US disclosed
US-20090309068-A1 NOVEL ELECTROLUMINESCENT POLYMERS FOR ELECTRONIC APPLICATIONS UDC IRELAND LIMITED (IE) 2009-12-17 US disclosed
US-20090309068-A1 NOVEL ELECTROLUMINESCENT POLYMERS FOR ELECTRONIC APPLICATIONS UDC IRELAND LIMITED (IE) 2009-12-17 US disclosed