Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.74 |
| ▸ | LMNA | P02545 | 5/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 2/20 | 0.70 |
| ▸ | NQO2 | P16083 | 1/20 | 0.70 |
| ▸ | RECQL | P46063 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.62 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31070199 | 1.00 | KDM4E (0.74) | KDM4EALDH1A1L3MBTL1LMNATDP1 | |
| SCHEMBL14076263 | 0.91 | ALDH1A1 (0.73) | KDM4EALDH1A1L3MBTL1LMNATDP1 | |
| SCHEMBL2867767 | 0.89 | MAPK14 (0.69) | KDM4EALDH1A1L3MBTL1LMNATDP1 | |
| SCHEMBL28459393 | 0.89 | ALDH1A1 (0.60) | KDM4EALDH1A1L3MBTL1LMNATDP1 | |
| SCHEMBL6304505 | 0.89 | KDM4E (0.62) | KDM4EALDH1A1L3MBTL1LMNATDP1 | |
| SCHEMBL10690882 | 0.88 | ALDH1A1 (0.63) | KDM4EALDH1A1L3MBTL1LMNATDP1 | |
| SCHEMBL12062005 | 0.85 | ALDH1A1 (0.76) | KDM4EALDH1A1L3MBTL1LMNATDP1 | |
| SCHEMBL15056743 | 0.85 | KDM4E (1.00) | KDM4EALDH1A1L3MBTL1LMNATDP1 | |
| SCHEMBL12341701 | 0.84 | ALDH1A1 (0.71) | KDM4EALDH1A1L3MBTL1LMNATDP1 | |
| SCHEMBL12964202 | 0.84 | KMT2A (0.73) | KDM4EALDH1A1L3MBTL1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116496-B | Synthetic method of quinoxaline heterocyclic derivative | 扬州大学 | 2021-12-31 | — | — | CN | disclosed |
| CN-111116496-A | Synthetic method of quinoxaline heterocyclic derivative | 扬州大学 | 2020-05-08 | — | — | CN | disclosed |
| EP-0562915-B1 | Heterocyclic chromenes and their use in ophthalmic optics | TRANSITIONS OPTICAL INC (US) | 2000-07-05 | — | — | EP | disclosed |
| US-5754271-A | PHOTOCHROMIC DYES FOR SUNGLASSES AND CONTACT LENSES | ESSILOR INTERNATIONAL (COMPAGNIE GENERAL D'OPTIQUE) (FR) | 1998-05-19 | — | — | US | disclosed |
| US-5631720-A | POLYMERIC LENS COMPRISING PHOTOCHROMIC COMPOUND COATINGS CHANGING COLOR UPON EXPOSURE TO ULTRAVIOLET RADIATION | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 1997-05-20 | — | — | US | disclosed |
| US-5527911-A | USEFUL IN OPHTHALMIC OPTICS | ESSILOR INTERNATIONAL (FR) | 1996-06-18 | — | — | US | disclosed |
| EP-0562915-A1 | Heterocyclic chromenes and their use in ophthalmic optics | ESSILOR INTERNATIONAL Compagnie Générale d'Optique (FR) | 1993-09-29 | — | — | EP | disclosed |
| EP-0220589-B1 | PHOTOPOLYMERISABLE COMPOUND AND REGISTRATION MATERIAL CONTAINING IT | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-22 | — | — | EP | disclosed |
| US-4737445-A | 2,3-DIHYDRO-1H-CYCLOPENTA(B)QUINOLINE | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-04-12 | — | — | US | disclosed |