SCHEMBL10330516

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10456699	0.93	TP53 (0.62)	LMNAMAPTTSHRMAPK1HPGD
	SCHEMBL10330506	0.90	TP53 (0.69)	LMNAMAPTTSHRMAPK1HPGD
	SCHEMBL8914355	0.87	TP53 (0.59)	LMNAMAPTTSHRMAPK1TP53
	SCHEMBL28556525	0.87	TP53 (0.59)	LMNAMAPTTSHRMAPK1TP53
	SCHEMBL29381824	0.86	TSHR (0.75)	LMNAMAPTTSHRMAPK1HPGD
	SCHEMBL150008	0.86	TSHR (0.75)	LMNAMAPTTSHRMAPK1HPGD
	SCHEMBL14818745	0.85	MAPK1 (0.65)	LMNAMAPTTSHRMAPK1TP53
	SCHEMBL10330501	0.83	TP53 (0.79)	LMNAMAPTTSHRMAPK1TP53
	SCHEMBL8101613	0.83	TP53 (0.78)	LMNAMAPTHPGDGAATP53
	SCHEMBL10330507	0.82	KMT2A (0.59)	LMNAMAPTTSHRMAPK1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.