Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20686097 | 0.87 | POLB (0.44) | POLBKDM4EATMCLCN2CYP2C19 | |
| SCHEMBL23843894 | 0.82 | CLCN2 (0.34) | POLBCLCN2CYP2C19RAB9ASMN1; SMN2 | |
| SCHEMBL8574363 | 0.81 | POLB (0.53) | POLBKDM4EATMCLCN2CYP2C19 | |
| SCHEMBL329566 | 0.80 | THRB (0.33) | CLCN2NPC1 | |
| SCHEMBL18888182 | 0.80 | ALDH1A1 (0.38) | POLBKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL22927509 | 0.80 | KDM4E (0.40) | POLBKDM4EATMCLCN2CYP2C19 | |
| Hydrochloric Acid SCHEMBL28447296 | 0.79 | POLB (0.52) | POLBKDM4EATMCLCN2CYP2C19 | |
| SCHEMBL10222679 | 0.74 | KDM4E (0.36) | POLBKDM4EATMCLCN2 | |
| SCHEMBL3695608 | 0.72 | THRB (0.48) | POLBKDM4EATMALDH1A1HPGD | |
| SCHEMBL9272886 | 0.72 | ALDH1A1 (0.39) | KDM4EATMALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3087069-B1 | COMPOUNDS USEFUL AS CCR9 MODULATORS | NORGINE BV (NL) | 2019-01-30 | — | — | EP | disclosed |
| US-8221657-B2 | Near infrared absorbing phthalocyanines and their use | BASF SE (DE) | 2012-07-17 | — | — | US | disclosed |
| US-20110236642-A1 | NEAR INFRARED ABSORBING PHTHALOCYANINES AND THEIR USE | PERI FRANCESCA | 2011-09-29 | — | — | US | disclosed |
| US-20100032608-A1 | NEAR INFRARED ABSORBING PHTHALOCYANINES AND THEIR USE | CIBA CORPORATION (US) | 2010-02-11 | — | — | US | disclosed |