Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.38 |
| ▸ | SRPK1 | Q96SB4 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.38 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 4/20 | 0.35 |
| ▸ | GSK3B | P49841 | 4/20 | 0.35 |
| ▸ | CCR9 | P51686 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2680858 | 0.93 | MEN1 (0.38) | KDM4CLIPEF10GSK3AGSK3B | |
| SCHEMBL1034169 | 0.85 | HIF1A (0.51) | HIF1AEPAS1SRPK1KDRSRPK2 | |
| SCHEMBL15943296 | 0.85 | MEN1 (0.38) | KDM4CLIPEF10GSK3AGSK3B | |
| SCHEMBL12153550 | 0.83 | GSK3B (0.38) | LIPEF10GSK3AGSK3BMAPT | |
| SCHEMBL4401609 | 0.82 | MAPK14 (0.38) | F10GSK3AGSK3BMAPTALDH1A1 | |
| SCHEMBL4442622 | 0.79 | HDAC4 (0.34) | F10GSK3AGSK3BMAPTMEN1 | |
| SCHEMBL1031737 | 0.78 | HIF1A (0.51) | HIF1AEPAS1SRPK1KDRSRPK2 | |
| SCHEMBL2681885 | 0.78 | F10 (0.44) | HIF1AEPAS1F10BRAFMEN1 | |
| Hydrochloric Acid SCHEMBL2681741 | 0.78 | F10 (0.43) | HIF1AEPAS1F10BRAFMEN1 | |
| Acetic Acid SCHEMBL2680690 | 0.76 | F10 (0.42) | HIF1AEPAS1F10BRAFMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011003684-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-01-13 | — | — | WO | disclosed |