Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 known ✓ | P35346 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 8/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | BRAF | P15056 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2681885 | 0.97 | F10 (0.44) | F10HIF1AEPAS1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2681741 | 0.96 | F10 (0.43) | F10HIF1AEPAS1MEN1KMT2A | |
| SCHEMBL2680721 | 0.92 | HIF1A (0.42) | F10HIF1AEPAS1MEN1KMT2A | |
| SCHEMBL1034169 | 0.90 | HIF1A (0.51) | F10HIF1AEPAS1SSTR5 | |
| SCHEMBL2681756 | 0.87 | F10 (0.44) | F10SSTR5MCHR1 | |
| SCHEMBL4401608 | 0.87 | F10 (0.44) | F10HDAC1MCHR1 | |
| SCHEMBL12153653 | 0.86 | MCHR1 (0.44) | F10HIF1AEPAS1MEN1KMT2A | |
| SCHEMBL1031737 | 0.84 | HIF1A (0.51) | HIF1AEPAS1SSTR5MCHR1 | |
| SCHEMBL15943296 | 0.84 | MEN1 (0.38) | F10HDAC1MEN1KMT2A | |
| SCHEMBL2680858 | 0.83 | MEN1 (0.38) | F10HDAC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451801-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-13 | — | — | EP | disclosed |
| US-8586593-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2013-11-19 | — | — | US | disclosed |
| US-20120115884-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115884-A1 | INSECTICIDAL COMPOUNDS | ACHE, C1R, C5 | SSTR5 2176/4885F10 1116/4885HIF1A 4471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.