Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 6/20 | 0.34 |
| ▸ | GSK3B | P49841 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2680858 | 0.92 | MEN1 (0.38) | MEN1KMT2AF10MAPK14HDAC4 | |
| SCHEMBL12153454 | 0.91 | GSK3B (0.39) | MEN1KMT2AMAPK14HDAC4ALDH1A1 | |
| SCHEMBL2681885 | 0.86 | F10 (0.44) | MEN1KMT2AF10 | |
| Hydrochloric Acid SCHEMBL2681741 | 0.85 | F10 (0.43) | MEN1KMT2AF10 | |
| SCHEMBL1033145 | 0.85 | HIF1A (0.38) | MEN1KMT2AF10ALDH1A1GAA | |
| Acetic Acid SCHEMBL2680690 | 0.84 | F10 (0.42) | MEN1KMT2AF10HDAC1 | |
| SCHEMBL12153550 | 0.81 | GSK3B (0.38) | MEN1KMT2AF10MAPK14LIPE | |
| SCHEMBL2680721 | 0.81 | HIF1A (0.42) | MEN1KMT2AF10GSK3B | |
| SCHEMBL4401609 | 0.81 | MAPK14 (0.38) | F10MAPK14ALDH1A1GAAGSK3A | |
| SCHEMBL12535747 | 0.80 | GSK3B (0.40) | MEN1KMT2AMAPK14GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451801-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-13 | — | — | EP | disclosed |