SCHEMBL10333368

SCHEMBL10333368

O=C(O)CCCCCNS(=O)(=O)c1ccc(C(=O)c2ccc(Cl)cc2)cc1

nearest known ligand 0.87

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TBXA2R P21731 2/20 0.66
ALDH1A1 P00352 1/20 0.66
FABP4 P15090 3/20 0.65
TBXAS1 P24557 4/20 0.60
PKM P14618 1/20 0.57
LMNA P02545 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10333962 1.00 TBXA2R (0.66) TBXA2RALDH1A1FABP4TBXAS1PKM
SCHEMBL10334130 1.00 TBXA2R (0.66) TBXA2RALDH1A1FABP4TBXAS1PKM
SCHEMBL9871736 0.93 TBXA2R (0.75) TBXA2RALDH1A1FABP4TBXAS1PKM
SCHEMBL9869922 0.93 TBXA2R (0.75) TBXA2RALDH1A1FABP4TBXAS1PKM
SCHEMBL9872542 0.93 TBXA2R (0.75) TBXA2RALDH1A1FABP4TBXAS1PKM
SCHEMBL9870233 0.93 TBXA2R (0.75) TBXA2RALDH1A1FABP4TBXAS1PKM
SCHEMBL9872413 0.93 TBXA2R (0.75) TBXA2RALDH1A1FABP4TBXAS1PKM
SCHEMBL9870095 0.93 TBXA2R (0.75) TBXA2RALDH1A1FABP4TBXAS1PKM
SCHEMBL9879916 0.93 TBXA2R (0.75) TBXA2RALDH1A1FABP4TBXAS1PKM
SCHEMBL10333940 0.88 ALDH1A1 (0.61) TBXA2RALDH1A1FABP4TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4980349-A ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTICOAGULANTS SANOFI (FR) 1990-12-25 US disclosed