Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | FABP4 | P15090 | 3/20 | 0.74 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870233 | 1.00 | TBXA2R (0.75) | TBXA2RALDH1A1FABP4TBXAS1LMNA | |
| SCHEMBL9870095 | 1.00 | TBXA2R (0.75) | TBXA2RALDH1A1FABP4TBXAS1LMNA | |
| SCHEMBL9871736 | 1.00 | TBXA2R (0.75) | TBXA2RALDH1A1FABP4TBXAS1LMNA | |
| SCHEMBL9872413 | 1.00 | TBXA2R (0.75) | TBXA2RALDH1A1FABP4TBXAS1LMNA | |
| SCHEMBL9872542 | 1.00 | TBXA2R (0.75) | TBXA2RALDH1A1FABP4TBXAS1LMNA | |
| SCHEMBL9869922 | 1.00 | TBXA2R (0.75) | TBXA2RALDH1A1FABP4TBXAS1LMNA | |
| SCHEMBL7384412 | 0.94 | FABP4 (0.72) | TBXA2RALDH1A1FABP4TBXAS1LMNA | |
| SCHEMBL10333368 | 0.93 | TBXA2R (0.66) | TBXA2RALDH1A1FABP4TBXAS1LMNA | |
| SCHEMBL10333962 | 0.93 | TBXA2R (0.66) | TBXA2RALDH1A1FABP4TBXAS1LMNA | |
| SCHEMBL10334130 | 0.93 | TBXA2R (0.66) | TBXA2RALDH1A1FABP4TBXAS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997847-A | Thromboxane A2 antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (DE) | 1991-03-05 | — | — | US | disclosed |
| EP-0304271-A2 | Omega-arylsulphonamidoalkanoic acids for treatment of thromboxane medited diseases | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-02-22 | — | — | EP | disclosed |