Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | RARA | P10276 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | TACR2 | P21452 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SHBG | P04278 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9805784 | 1.00 | RARB (0.56) | RARBALDH1A1RARAMEN1MAPT | |
| SCHEMBL9324237 | 0.94 | ESR1 (0.57) | RARBALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL9808869 | 0.93 | ESR1 (0.60) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL13219975 | 0.93 | ESR1 (0.60) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL9478972 | 0.93 | ESR1 (0.60) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL3959914 | 0.93 | ESR1 (0.60) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL9479954 | 0.93 | ESR1 (0.60) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL6130141 | 0.93 | ESR1 (0.60) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL1133495 | 0.93 | ESR1 (0.60) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL3952158 | 0.89 | CA2 (0.52) | RARBALDH1A1ESR1ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916074-A | ENZYMATIC TRANS ESTERIFICATION OF ALCOHOL WITH TRIGLYCERIDES; PSEUDOMONAS-DERIVED ENZYME | CHISSO CORPORATION (JP) | 1990-04-10 | — | — | US | disclosed |