Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 4/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3244128 | 0.82 | — | — | |
| SCHEMBL9015208 | 0.68 | ALDH1A1 (0.36) | LMNAALDH1A1 | |
| SCHEMBL6800419 | 0.64 | L3MBTL1 (0.41) | LMNAFBP1ALDH1A1 | |
| SCHEMBL7015023 | 0.64 | GAA (0.45) | LMNAALDH1A1 | |
| SCHEMBL28113971 | 0.64 | ALDH1A1 (0.36) | LMNAFBP1ALDH1A1 | |
| SCHEMBL27977646 | 0.63 | — | — | |
| SCHEMBL27739596 | 0.63 | — | — | |
| SCHEMBL28309527 | 0.63 | — | — | |
| SCHEMBL3934072 | 0.63 | — | — | |
| SCHEMBL27592302 | 0.60 | PARP1 (0.36) | LMNAGLAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2237971-A | — | — | None | — | — | JP | disclosed |
| JP-H02237971-A | CONTROL OF HARMFUL LIFE | AMERICAN CYANAMID CO | 1990-09-20 | — | — | JP | disclosed |