Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209691 | 0.88 | DPP4 (0.55) | KMT2AALDH1A1TSHRDPP4MEN1 | |
| SCHEMBL10335879 | 0.87 | ACE (0.50) | DPP4ACEACE2 | |
| SCHEMBL10335836 | 0.85 | F2 (0.51) | ACEACE2 | |
| SCHEMBL7278569 | 0.84 | KMT2A (0.49) | KMT2AALDH1A1TSHRF2RL1DPP4 | |
| SCHEMBL9372814 | 0.83 | HPGD (0.58) | KMT2AALDH1A1DPP4MEN1L3MBTL1 | |
| SCHEMBL7475648 | 0.83 | HPGD (0.58) | KMT2AALDH1A1DPP4MEN1L3MBTL1 | |
| SCHEMBL3504947 | 0.83 | HPGD (0.58) | KMT2AALDH1A1DPP4MEN1L3MBTL1 | |
| SCHEMBL7293220 | 0.83 | ACE (0.57) | ALDH1A1ACEACE2 | |
| SCHEMBL6786409 | 0.83 | ACE (0.57) | ALDH1A1ACEACE2 | |
| SCHEMBL9702219 | 0.82 | DPP4 (0.49) | DPP4ACEDGAT1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977180-A | ANTIAMNESIA AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-12-11 | — | — | US | disclosed |
| US-4952601-A | Fungicidal 3-cyano-4-phenyl-pyrrole derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1990-08-28 | — | — | US | disclosed |