Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10425827 | 0.88 | HPGD (0.51) | KMT2AALDH1A1TSHRFKBP1AKDM4E | |
| SCHEMBL7284906 | 0.87 | PRCP (0.44) | KMT2AALDH1A1HPGDHRH3MEN1 | |
| SCHEMBL7275441 | 0.85 | ALDH1A1 (0.50) | KMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL7279235 | 0.85 | PRCP (0.44) | KMT2AALDH1A1HPGDGAAHRH3 | |
| SCHEMBL7284993 | 0.84 | NPC1 (0.47) | KMT2AHPGDMEN1NPC1RAB9A | |
| SCHEMBL10334010 | 0.84 | KMT2A (0.49) | KMT2AALDH1A1TSHRF2RL1FKBP1A | |
| SCHEMBL7267256 | 0.82 | HRH3 (0.53) | KMT2AALDH1A1TSHRGAAHRH3 | |
| SCHEMBL7284635 | 0.82 | OPRD1 (0.44) | HRH3DPP4FAPDPP8DPP9 | |
| SCHEMBL7267087 | 0.81 | ALDH1A1 (0.48) | KMT2AALDH1A1HPGDGAAHRH3 | |
| SCHEMBL7279739 | 0.81 | UTS2R (0.43) | FKBP1AHRH3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277588-B1 | PROLINAL DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-03-24 | — | — | EP | claimed |
| EP-0277588-A1 | Prolinal derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-08-10 | — | — | EP | claimed |
| US-5091406-A | Cognition activators | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-02-25 | — | — | US | disclosed |