Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.49 |
| ▸ | ACE | P12821 | 10/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10335879 | 0.85 | ACE (0.50) | DPP4ACEACE2CHRM2CHRM4 | |
| SCHEMBL10335836 | 0.85 | F2 (0.51) | ACEACE2CHRM2CHRM4CHRM1 | |
| SCHEMBL7284635 | 0.84 | OPRD1 (0.44) | DPP4OPRD1 | |
| SCHEMBL7293220 | 0.83 | ACE (0.57) | ACEACE2CHRM2CHRM4CHRM1 | |
| SCHEMBL6786409 | 0.83 | ACE (0.57) | ACEACE2CHRM2CHRM4CHRM1 | |
| SCHEMBL10334010 | 0.82 | KMT2A (0.49) | DPP4ACEACE2DGAT1 | |
| Trifluoroacetic Acid SCHEMBL6789002 | 0.78 | DPP4 (0.46) | DPP4ACEACE2OPRD1 | |
| SCHEMBL3858374 | 0.78 | ACE (0.57) | DPP4ACEACE2CHRM2CHRM4 | |
| SCHEMBL3144462 | 0.78 | ACE (0.64) | ACEACE2CHRM2CHRM4CHRM1 | |
| SCHEMBL5742165 | 0.78 | ACE (0.64) | ACEACE2CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091406-A | Cognition activators | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-02-25 | — | — | US | disclosed |