Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 10/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27473587 | 0.86 | NCEH1 (0.67) | NCEH1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL30710587 | 0.85 | MAPT (0.58) | NCEH1HTTMAPTSLC22A6TSHR | |
| SCHEMBL12199931 | 0.85 | MAPT (0.58) | NCEH1HTTMAPTSLC22A6TSHR | |
| SCHEMBL29963395 | 0.84 | NCEH1 (0.53) | NCEH1HTTMEN1NPC1MAPT | |
| SCHEMBL9683874 | 0.84 | NCEH1 (0.51) | NCEH1HTTNPC1MAPTRAB9A | |
| SCHEMBL6142391 | 0.84 | NCEH1 (0.51) | NCEH1HTTMEN1NPC1MAPT | |
| SCHEMBL9488962 | 0.84 | HTT (0.54) | NCEH1HTTMAPTKMT2ASLC22A6 | |
| SCHEMBL25969910 | 0.83 | NCEH1 (0.63) | NCEH1MEN1NPC1MAPTRAB9A | |
| SCHEMBL23930399 | 0.82 | NCEH1 (0.72) | NCEH1HTTNPC1MAPTRAB9A | |
| SCHEMBL29946533 | 0.82 | NCEH1 (0.69) | NCEH1HTTNPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247608-A1 | SMALL MOLECULE INHIBITORS OF A PROTEIN COMPLEX | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-12-10 | — | — | WO | disclosed |
| CN-109312025-A | The method for being used to prepare organic charge transport film | 陶氏环球技术有限责任公司 | 2019-02-05 | — | — | CN | disclosed |
| US-20100286360-A1 | POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20100286360-A1 | POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20070032525-A1 | Piperidine derivatives having ccr3 antagonism | TEIJIN LIMITED, A JAPANESE BODY CORPORATE (JP) | 2007-02-08 | — | — | US | disclosed |
| CN-1724597-A | Phase change inks | XEROX CORP (US) | 2006-01-25 | — | — | CN | disclosed |
| US-4904752-A | Liquid crystal copolyester having blocked molecular chain terminal | POLYPLASTICS CO., LTD. (JP) | 1990-02-27 | — | — | US | disclosed |
| EP-0269321-A2 | Liquid crystal copolyesters having a blocked terminal of its molecular chain | POLYPLASTICS CO. LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286360-A1 | POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME | IGF1R, SCO2, CRY1 | NCEH1 3255/4885HTT 4114/4885MEN1 725/4885 |
| US-20070032525-A1 | Piperidine derivatives having ccr3 antagonism | CCR3, CCR1, CCR4 | NCEH1 726/4885HTT 3359/4885MEN1 3556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.