Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | NCEH1 | Q6PIU2 | 7/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | ADK | P55263 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | WDR5 | P61964 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GGT1 | P19440 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12199931 | 1.00 | MAPT (0.58) | MAPTNCEH1HTTNPSR1GAA | |
| SCHEMBL16237145 | 0.93 | MAPT (0.71) | MAPTNCEH1HTTNPSR1GAA | |
| SCHEMBL14118237 | 0.92 | NCEH1 (0.50) | MAPTNCEH1HTTNPSR1GAA | |
| SCHEMBL15247643 | 0.92 | PIM1 (0.54) | MAPTNCEH1HTTNPSR1GAA | |
| Hydrochloric Acid SCHEMBL16236798 | 0.91 | MAPT (0.53) | MAPTNCEH1HTTNPSR1GAA | |
| SCHEMBL27994957 | 0.90 | NCEH1 (0.48) | MAPTNCEH1HTTNPSR1GAA | |
| SCHEMBL16236807 | 0.89 | MAPT (0.47) | MAPTNCEH1HTTNPSR1GAA | |
| SCHEMBL16236334 | 0.89 | MAPT (0.50) | MAPTNCEH1HTTNPSR1GAA | |
| SCHEMBL30448667 | 0.89 | GSK3B (0.59) | MAPTNCEH1HTTNPSR1GAA | |
| SCHEMBL4366187 | 0.89 | GSK3B (0.59) | MAPTNCEH1HTTNPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240150382-A1 | SILYL-BIARYL PHOSPHORAMIDITES AND METHODS OF MAKING | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2024-05-09 | — | — | US | disclosed |
| US-11840550-B2 | Silyl-biaryl phosphoramidites and methods of making | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-12-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11840550-B2 | Silyl-biaryl phosphoramidites and methods of making | PAICS, PGLS, SCLY | MAPT 3825/4885NCEH1 4505/4885HTT 4415/4885 |
| US-20240150382-A1 | SILYL-BIARYL PHOSPHORAMIDITES AND METHODS OF MAKING | PAICS, PGLS, SCLY | MAPT 3825/4885NCEH1 4505/4885HTT 4415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.